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Copz1 Gene Detail
Summary
  • Symbol
    Copz1
  • Name
    coatomer protein complex, subunit zeta 1
  • Synonyms
    5930435A22Rik, D4Ertd360e, nonclathrin coat protein zeta1-COP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1929063
    NCBI Gene: 56447
  • Gene Overview
    MyGene.info: COPZ1
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:103272834-103299869 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 58.74 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    158 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1929063
protein coding gene Chr15:103272714-103299869 (.)
129S1/SvImJ MGP_129S1SvImJ_G0022437
protein coding gene Chr15:105528966-105566574 (+)
A/J MGP_AJ_G0022399
protein coding gene Chr15:101356575-101383839 (+)
AKR/J MGP_AKRJ_G0022374
protein coding gene Chr15:104430341-104464166 (+)
BALB/cJ MGP_BALBcJ_G0022403
protein coding gene Chr15:101402604-101428888 (+)
C3H/HeJ MGP_C3HHeJ_G0022170
protein coding gene Chr15:104528114-104556396 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022852
protein coding gene Chr15:109417626-109449577 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020375
protein coding gene Chr15:97119842-97146119 (+)
CAST/EiJ MGP_CASTEiJ_G0021696
protein coding gene Chr15:105396188-105426502 (+)
CBA/J MGP_CBAJ_G0022139
protein coding gene Chr15:113268789-113299064 (+)
DBA/2J MGP_DBA2J_G0022270
protein coding gene Chr15:100633311-100659846 (+)
FVB/NJ MGP_FVBNJ_G0022246
protein coding gene Chr15:99693093-99719530 (+)
LP/J MGP_LPJ_G0022339
protein coding gene Chr15:105674202-105700451 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022268
protein coding gene Chr15:116768142-116801186 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022864
protein coding gene Chr15:104473302-104499342 (+)
PWK/PhJ MGP_PWKPhJ_G0021436
protein coding gene Chr15:100811378-100839406 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021268
protein coding gene Chr15:104306604-104335574 (+)
WSB/EiJ MGP_WSBEiJ_G0021746
protein coding gene Chr15:105090347-105120578 (+)



Homology
more
  • Human Ortholog
    COPZ1, coatomer protein complex subunit zeta 1
  • Vertebrate Orthologs
    7
  • Human Ortholog
    COPZ1, coatomer protein complex subunit zeta 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CGI-120, COPZ, HSPC181, zeta1-COP, zeta-COP
  • Links
    NCBI Gene ID: 22818
    neXtProt AC: NX_P61923
    UniProt: P61923

  • Chr Location
    12q13.13; chr12:54325090-54351851 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56447 NCBI Gene Model | MGI Sequence Detail 27036 C57BL/6J ±  kb
transcript NM_001357748 RefSeq | MGI Sequence Detail 1924 C57BL/6  
polypeptide P61924 UniProt | EBI | MGI Sequence Detail 177 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 275
    Genomic 1
    cDNA 273
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1196438, MGI:1915335, MGI:2145892
References
more
  • Summaries
    All 36
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:197389 Slater LH, et al., CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9932-7

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory