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Polr1e
Gene Detail
Symbol

Name
ID
Polr1e
polymerase (RNA) I polypeptide E
MGI:1929022
Synonyms
53kDa, D030019D19Rik, Paf53, Praf1
Feature Type
protein coding gene
Genetic Map
Chromosome 4
23.67 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:45018583-45036565 bp, + strand
From VEGA annotation of GRCm38

  17983 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41486  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: POLR1E
Protein SuperFamily: DNA-directed RNA polymerase I, RPA49/RPF53 subunits
Gene Tree: Polr1e

Human
homologs
POLR1E, polymerase (RNA) I polypeptide E, 53kDa
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 64425
neXtProt AC: NX_Q9GZS1

Human Synonyms: PAF53, PRAF1

Human Chr (Location): 9p13.2; chr9:37485935-37503697 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Polr1e interacts with 173 markers (Mir1a-1, Mir1a-2, Mir17, ...)
Expression
Literature Summary: (3 records)
Data Summary: Results (141)    Tissues (140)    Images (18)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 141
cDNA source data(52)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase polr1e ; ZFIN polr1e    NEW 
Molecular
reagents
All nucleic(53) cDNA(52) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000007388 (Evidence)
Ensembl Gene Model ENSMUSG00000028318 (Evidence)
Entrez Gene 64424 (Evidence)
UniGene 282932
DFCI TC1778181, TC1758618, TC1595415, TC1578119
DoTS DT.94135286, DT.531676, DT.99838899, DT.101740886
NIA Mouse Gene Index U004267
Consensus CDS Project CCDS18131.1, CCDS71378.1
International Mouse Phenotyping Consortium Status Polr1e
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007388 VEGA Gene Model | MGI Sequence Detail 17983 C57BL/6J ±  kb
transcript OTTMUST00000017089 VEGA | MGI Sequence Detail 1724 Not Applicable 
polypeptide OTTMUSP00000007896 VEGA | MGI Sequence Detail 482 Not Applicable 

For the selected sequences
All sequences(51) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(95 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009668 RNA polymerase I associated factor, A49-like
Protein Ontology PR:000012986 DNA-directed RNA polymerase I subunit RPA49
References
(Earliest) J:35801 Seither P, et al., Molecular cloning of RPA2, the gene encoding the second largest subunit of mouse RNA polymerase I. Genomics. 1996 Oct 1;37(1):135-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(37)
Other
accession IDs
MGI:2140482, MGI:2444374

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory