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Polr1e
Gene Detail
Symbol

Name
ID
Polr1e
polymerase (RNA) I polypeptide E
MGI:1929022
Synonyms
53kDa, D030019D19Rik, Paf53, Praf1
Feature Type
protein coding gene
Genetic Map
Chromosome 4
23.67 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr4:45018583-45036565 bp, + strand
From VEGA annotation of GRCm38

  17983 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41486  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: DNA-directed RNA polymerase I, RPA49/RPF53 subunits
Gene Tree: Polr1e

Human
homologs
Human Homolog POLR1E, polymerase (RNA) I polypeptide E, 53kDa
NCBI Gene ID 64425
neXtProt AC  NX_Q9GZS1
Human Synonyms  PAF53, PRAF1
Human Chr (Location)  9p13.2; chr9:37485935-37503697 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Polr1e interacts with 174 markers (Mir1a-1, Mir1a-2, Mir17, ...)
Expression
Literature Summary: (3 records)
Data Summary: Results (141)    Tissues (140)    Images (18)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 141
cDNA source data(52)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(53) cDNA(52) Primer pair(1)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000007388 (Evidence)
Ensembl Gene ModelENSMUSG00000028318 (Evidence)
Entrez Gene64424 (Evidence)
UniGene282932
DFCITC1758618, TC1595415, TC1578119, TC1778181
DoTSDT.101740886, DT.531676, DT.94135286, DT.99838899
NIA Mouse Gene IndexU004267
Consensus CDS ProjectCCDS18131.1, CCDS71378.1
International Mouse Knockout Project StatusPolr1e
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000007388 VEGA Gene Model | MGI Sequence Detail 17983 C57BL/6J ±  kb
transcript OTTMUST00000017089 VEGA | MGI Sequence Detail 1724 Not Applicable 
polypeptide OTTMUSP00000007896 VEGA | MGI Sequence Detail 482 Not Applicable 

For the selected sequences
All sequences(53) RefSeq(4) UniProt(5)
Polymorphisms
SNPs within 2kb(95 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009668 RNA polymerase I associated factor, A49-like
Protein Ontology PR:000012986 DNA-directed RNA polymerase I subunit RPA49
References
(Earliest) J:35801 Seither P, et al., Molecular cloning of RPA2, the gene encoding the second largest subunit of mouse RNA polymerase I. Genomics. 1996 Oct 1;37(1):135-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)
Other
accession IDs
MGI:2140482, MGI:2444374

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory