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Ccl24 Gene Detail
Summary
  • Symbol
    Ccl24
  • Name
    chemokine (C-C motif) ligand 24
  • Synonyms
    CKb-6, eotaxin-2, MPIF-2, Scya24
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928953
    NCBI Gene: 56221
Location & Maps
more
  • Sequence Map
    Chr5:135569937-135573049 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3113 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 75.28 cM, cytoband G1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    CCL24, C-C motif chemokine ligand 24
  • Vertebrate Orthologs
    7
  • Human Ortholog
    CCL24, C-C motif chemokine ligand 24
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Ckb-6, MPIF2, MPIF-2, SCYA24
  • Links
    NCBI Gene ID: 6369
    neXtProt AC: NX_O00175

  • Chr Location
    7q11.23; chr7:75811429-75823356 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 2 genetic backgrounds
    5 phenotypes from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    3
  • Gene trapped
    1
  • Targeted
    2
Mutant mice are born at the expected Mendelian frequency and appear healthy and normal.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000055905 VEGA Gene Model | MGI Sequence Detail 3113 C57BL/6J ±  kb
transcript OTTMUST00000138287 VEGA | MGI Sequence Detail 1295 Not Applicable  
polypeptide OTTMUSP00000072716 VEGA | MGI Sequence Detail 119 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    55 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000001996 C-C motif chemokine 24
  • InterPro Domains
    IPR000827 CC chemokine, conserved site
    IPR001811 Chemokine interleukin-8-like domain
Molecular
Reagents
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  • All nucleic 8
    cDNA 8

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Gene Ontology 8
    Phenotypes 9
  • Earliest
    J:66327 Zimmermann N, et al., Murine eotaxin-2: A constitutive eosinophil chemokine induced by allergen challenge and IL-4 overexpression. J Immunol. 2000 Nov 15;165(10):5839-46
  • Latest
    J:222328 Makita N, et al., IL-10 enhances the phenotype of M2 macrophages induced by IL-4 and confers the ability to increase eosinophil migration. Int Immunol. 2015 Mar;27(3):131-41

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory