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Ccl24 Gene Detail
Summary
  • Symbol
    Ccl24
  • Name
    chemokine (C-C motif) ligand 24
  • Synonyms
    CKb-6, eotaxin-2, MPIF-2, Scya24
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928953
    NCBI Gene: 56221
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:135569937-135573049 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 75.28 cM, cytoband G1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    55 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928953
protein coding gene Chr5:135569937-135573123 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030185
protein coding gene Chr5:140120863-140123975 (-)
A/J MGP_AJ_G0030153
protein coding gene Chr5:134125074-134128186 (-)
AKR/J MGP_AKRJ_G0030086
protein coding gene Chr5:138470946-138474058 (-)
BALB/cJ MGP_BALBcJ_G0030163
protein coding gene Chr5:135462257-135465369 (-)
C3H/HeJ MGP_C3HHeJ_G0029879
protein coding gene Chr5:139036886-139039998 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030616
protein coding gene Chr5:145345722-145348832 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027839
protein coding gene Chr5:128407075-128410446 (-)
CAST/EiJ MGP_CASTEiJ_G0029288
protein coding gene Chr5:138444456-138447594 (-)
CBA/J MGP_CBAJ_G0029849
protein coding gene Chr5:151029943-151033055 (-)
DBA/2J MGP_DBA2J_G0030000
protein coding gene Chr5:134017423-134020533 (-)
FVB/NJ MGP_FVBNJ_G0029955
protein coding gene Chr5:133160860-133163972 (-)
LP/J MGP_LPJ_G0030088
protein coding gene Chr5:140564110-140567222 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029987
protein coding gene Chr5:154019441-154022553 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030656
protein coding gene Chr5:138228664-138231776 (-)
PWK/PhJ MGP_PWKPhJ_G0029003
protein coding gene Chr5:133062172-133065275 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028838
protein coding gene Chr5:135777870-135781015 (-)
WSB/EiJ MGP_WSBEiJ_G0029362
protein coding gene Chr5:138966735-138969847 (-)



Homology
more
  • Human Ortholog
    CCL24, C-C motif chemokine ligand 24
  • Vertebrate Orthologs
    7
  • Human Ortholog
    CCL24, C-C motif chemokine ligand 24
    Orthology source: HomoloGene, HGNC
  • Synonyms
    Ckb-6, MPIF2, MPIF-2, SCYA24
  • Links
    NCBI Gene ID: 6369
    neXtProt AC: NX_O00175
    UniProt: O00175

  • Chr Location
    7q11.23; chr7:75810825-75823356 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 2 genetic backgrounds
    5 phenotypes from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mutant mice are born at the expected Mendelian frequency and appear healthy and normal.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000004814 Ensembl Gene Model | MGI Sequence Detail 3113 C57BL/6J ±  kb
transcript ENSMUST00000004936 Ensembl | MGI Sequence Detail 1295 Not Applicable  
polypeptide ENSMUSP00000004936 Ensembl | MGI Sequence Detail 119 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 3
References
more
  • Summaries
    All 42
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:66327 Zimmermann N, et al., Murine eotaxin-2: A constitutive eosinophil chemokine induced by allergen challenge and IL-4 overexpression. J Immunol. 2000 Nov 15;165(10):5839-46
  • Latest
    J:246682 Kannan Y, et al., TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus. PLoS Pathog. 2017 Jul;13(7):e1006536

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory