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Tacc2 Gene Detail
Summary
  • Symbol
    Tacc2
  • Name
    transforming, acidic coiled-coil containing protein 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928899
    NCBI Gene: 57752
  • Gene Overview
    MyGene.info: TACC2
Location & Maps
more
  • Sequence Map
    Chr7:130577438-130764785 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      187348 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 73.19 cM, cytoband F4
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    TACC2, transforming acidic coiled-coil containing protein 2
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TACC2, transforming acidic coiled-coil containing protein 2
    Orthology source: HomoloGene
  • Synonyms
    AZU-1, ECTACC
  • Links
    NCBI Gene ID: 10579
    neXtProt AC: NX_O95359

  • Chr Location
    10q26; chr10:121989174-122254545 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Homozygous null mice are healthy and fertile and do not display any increase in tumorigenesis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000059551 VEGA Gene Model | MGI Sequence Detail 187348 C57BL/6J ±  kb
transcript OTTMUST00000146110 VEGA | MGI Sequence Detail 9029 Not Applicable  
polypeptide OTTMUSP00000076124 VEGA | MGI Sequence Detail 2879 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1278 from dbSNP Build 142
Protein
Information
less
  • UniProt
    16 Sequences
  • Protein Ontology
    PR:000016007 transforming acidic coiled-coil-containing protein 2
  • InterPro Domains
    IPR007707 Transforming acidic coiled-coil-containing protein
Molecular
Reagents
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  • All nucleic 44
    cDNA 43
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 40
    Developmental Gene Expression 8
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:233777 Ray JP, et al., The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. Immunity. 2015 Oct 20;43(4):690-702

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory