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Krt81
Gene Detail
Symbol

Name
ID
Krt81
keratin 81
MGI:1928858
Synonyms
Krt2-19
Feature Type
protein coding gene
Genetic Map
Chromosome 15
56.90 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr15:101459061-101463765 bp, - strand
From NCBI annotation of GRCm38

  4705 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55645  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 2 dog

Gene Tree: Krt81

Human
homologs
Human Homolog KRT81, keratin 81
NCBI Gene ID 3887
neXtProt AC  NX_Q14533
Human Synonyms  ghHkb1, Hb-1, HB1, hHAKB2-1, KRTHB1, MLN137
Human Chr (Location)  12q13; chr12:52285913-52291515 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human KRT81
Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Radiation induced(1) Targeted(3)
Genomic Mutations involving Krt81 (2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Krt81 interacts with 57 markers (Mir16-1, Mir16-2, Mir17, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (6 annotations)
Process biological_process
Component extracellular space, intermediate filament, ...
Function structural molecule activity
External Resources: FuncBase
Expression
cDNA source data(2)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) Genomic(9) cDNA(2)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000067615 (Evidence)
Entrez Gene64818 (Evidence)
DFCITC1665868
DoTSDT.497233, DT.55114950, DT.55188295
Consensus CDS ProjectCCDS49734.1
International Mouse Knockout Project StatusKrt81
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 64818 NCBI Gene Model | MGI Sequence Detail 4705 C57BL/6J ±  kb
transcript NM_001166157 RefSeq | MGI Sequence Detail 1857 C57BL/6 
polypeptide Q9ERE2 UniProt | EBI | MGI Sequence Detail 481 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(26 from dbSNP Build 137)    SNPs within 2kb including multiple locations(36)
Protein-related
information
ResourceIDDescription
InterPro IPR001664 Intermediate filament protein
InterPro IPR018039 Intermediate filament protein, conserved site
InterPro IPR003054 Type II keratin
Graphical View of Protein Domain Structure
References
(Earliest) J:79964 Poirier C, et al., Hague (Hag). A new mouse hair mutation with an unstable semidominant allele. Genetics. 2002 Oct;162(2):831-40
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(25)
Other
accession IDs
MGI:2145922

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory