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Krt81 Gene Detail
Summary
  • Symbol
    Krt81
  • Name
    keratin 81
  • Synonyms
    Krt2-19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928858
    NCBI Gene: 64818
  • Gene Overview
    MyGene.info: KRT81
Location & Maps
more
  • Sequence Map
    Chr15:101459061-101463765 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4705 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 56.90 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    KRT81, keratin 81
  • Vertebrate Orthologs
    8
  • Human Ortholog
    KRT81, keratin 81
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ghHkb1, Hb-1, HB1, hHAKB2-1, KRTHB1, MLN137
  • Links
    NCBI Gene ID: 3887
    neXtProt AC: NX_Q14533
    UniProt: Q14533

  • Chr Location
    12q13.13; chr12:52285913-52291515 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human KRT81 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    26 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 64818 NCBI Gene Model | MGI Sequence Detail 4705 C57BL/6J ±  kb
transcript NM_001166157 RefSeq | MGI Sequence Detail 1857 C57BL/6  
polypeptide Q9ERE2 UniProt | EBI | MGI Sequence Detail 481 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    21 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001664 Intermediate filament protein
    IPR018039 Intermediate filament protein, conserved site
    IPR003054 Keratin, type II
    IPR032444 Keratin type II head
Molecular
Reagents
less
  • All nucleic 11
    Genomic 9
    cDNA 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145922
References
more
  • Summaries
    All 45
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 3
    Phenotypes 26
  • Earliest
    J:13437 Bangham JW, Hairy ears, Eh. Mouse News Lett. 1965;33:68
  • Latest
    J:239434 Fleger-Weckmann A, et al., Deletion of the epidermis derived laminin gamma1 chain leads to defects in the regulation of late hair morphogenesis. Matrix Biol. 2016 Dec;56:42-56

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory