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Krt81 Gene Detail
Summary
  • Symbol
    Krt81
  • Name
    keratin 81
  • Synonyms
    Krt2-19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928858
    NCBI Gene: 64818
  • Gene Overview
    MyGene.info: KRT81
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:101459061-101463751 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 56.90 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    21 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928858
protein coding gene Chr15:101459061-101463765 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022374
protein coding gene Chr15:103527471-103531822 (-)
A/J MGP_AJ_G0022336
protein coding gene Chr15:99427886-99432590 (-)
AKR/J MGP_AKRJ_G0022312
protein coding gene Chr15:102457058-102462163 (-)
BALB/cJ MGP_BALBcJ_G0022340
protein coding gene Chr15:99532008-99537434 (-)
C3H/HeJ MGP_C3HHeJ_G0022109
protein coding gene Chr15:102541820-102549278 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022788
protein coding gene Chr15:107385868-107392294 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020313
protein coding gene Chr15:95155847-95160580 (-)
CAST/EiJ MGP_CASTEiJ_G0021635
protein coding gene Chr15:103413823-103420886 (-)
CBA/J MGP_CBAJ_G0022079
protein coding gene Chr15:111107309-111115305 (-)
DBA/2J MGP_DBA2J_G0022206
protein coding gene Chr15:98762621-98767987 (-)
FVB/NJ MGP_FVBNJ_G0022185
protein coding gene Chr15:97813933-97821019 (-)
LP/J MGP_LPJ_G0022277
protein coding gene Chr15:103668067-103675652 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022206
protein coding gene Chr15:114780348-114786224 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022802
protein coding gene Chr15:102496022-102500267 (-)
PWK/PhJ MGP_PWKPhJ_G0021374
protein coding gene Chr15:98921775-98930085 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021206
protein coding gene Chr15:102385610-102393054 (-)
WSB/EiJ MGP_WSBEiJ_G0021684
protein coding gene Chr15:103127329-103136297 (-)



Homology
more
  • Human Ortholog
    KRT81, keratin 81
  • Vertebrate Orthologs
    8
  • Human Ortholog
    KRT81, keratin 81
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ghHkb1, Hb-1, HB1, hHAKB2-1, KRTHB1, MLN137
  • Links
    NCBI Gene ID: 3887
    neXtProt AC: NX_Q14533
    UniProt: Q14533

  • Chr Location
    12q13.13; chr12:52285913-52291515 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with human KRT81 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    26 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067615 Ensembl Gene Model | MGI Sequence Detail 4691 C57BL/6J ±  kb
transcript ENSMUST00000061185 Ensembl | MGI Sequence Detail 1843 Not Applicable  
polypeptide ENSMUSP00000056525 Ensembl | MGI Sequence Detail 481 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • InterPro Domains
    IPR001664 Intermediate filament protein
    IPR018039 Intermediate filament protein, conserved site
    IPR039008 Intermediate filament, rod domain
    IPR003054 Keratin, type II
    IPR032444 Keratin type II head
Molecular
Reagents
less
  • All nucleic 12
    Genomic 9
    cDNA 3

    Microarray probesets 4
Other
Accession IDs
less
MGI:2145922
References
more
  • Summaries
    All 45
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 2
    Phenotypes 26
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:239434 Fleger-Weckmann A, et al., Deletion of the epidermis derived laminin gamma1 chain leads to defects in the regulation of late hair morphogenesis. Matrix Biol. 2016 Dec;56:42-56

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory