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Pfdn5
Gene Detail
Symbol

Name
ID
Pfdn5
prefoldin 5
MGI:1928753
Synonyms
1190001O17Rik, 1700010A06Rik, c-myc binding protein MM-1, D15Ertd697e, EIG-1, MM-1
Feature Type
protein coding gene
Genetic Map
Chromosome 15
57.48 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:102326116-102331873 bp, + strand
From VEGA annotation of GRCm38

  5758 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1972  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PFDN5
Protein SuperFamily: prefoldin alpha subunit
Gene Tree: Pfdn5

Human
homologs
PFDN5, prefoldin subunit 5
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 5204
neXtProt AC: NX_Q99471

Human Synonyms: MM1, MM-1, PFD5

Human Chr (Location): 12q12; chr12:53295451-53299450 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Chemically induced (ENU)(1) Gene trapped(8) Radiation induced(1) Targeted(2)
Genomic Mutations involving Pfdn5 (1)
Incidental mutations (data from APF )
 
Mice homozygous for an ENU-induced mutation exhibit photoreceptor degeneration, central nervous system abnormalities, and male infertility.
 
Phenotype Images(2)
Interactions
Pfdn5 interacts with 51 markers (Mir15a, Mir129-1, Mir129-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
cDNA source data(213)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase pfdn5 ; ZFIN pfdn5    NEW 
Molecular
reagents
All nucleic(214) cDNA(213) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene Model OTTMUSG00000035798 (Evidence)
Ensembl Gene Model ENSMUSG00000001289 (Evidence)
Entrez Gene 56612 (Evidence)
UniGene 158264
DFCI TC1643251, TC1572180
Consensus CDS Project CCDS37227.1
International Mouse Phenotyping Consortium Status Pfdn5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035798 VEGA Gene Model | MGI Sequence Detail 5758 C57BL/6J ±  kb
transcript OTTMUST00000091649 VEGA | MGI Sequence Detail 1062 Not Applicable 
polypeptide OTTMUSP00000050496 VEGA | MGI Sequence Detail 154 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(3) UniProt(8)
Polymorphisms
SNPs within 2kb(70 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009053 Prefoldin
InterPro IPR011599 Prefoldin alpha subunit
InterPro IPR004127 Prefoldin subunit
Protein Ontology PR:000012575 prefoldin subunit 5
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:203848 Abe A, et al., Prefoldin plays a role as a clearance factor in preventing proteasome inhibitor-induced protein aggregation. J Biol Chem. 2013 Sep 27;288(39):27764-76
All references(37)
Other
accession IDs
MGI:1277126, MGI:1913474, MGI:1916585

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory