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Pfdn5
Gene Detail
Symbol

Name
ID
Pfdn5
prefoldin 5
MGI:1928753
Synonyms
1190001O17Rik, 1700010A06Rik, c-myc binding protein MM-1, D15Ertd697e, EIG-1, MM-1
Feature Type
protein coding gene
Genetic Map
Chromosome 15
57.48 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr15:102326116-102331873 bp, + strand
From VEGA annotation of GRCm38

  5758 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1972  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: prefoldin alpha subunit
Gene Tree: Pfdn5

Human
homologs
Human Homolog PFDN5, prefoldin subunit 5
NCBI Gene ID 5204
neXtProt AC  NX_Q99471
Human Synonyms  MM1, MM-1, PFD5
Human Chr (Location)  12q12; chr12:53295451-53299450 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(12) : Chemically induced (ENU)(1) Gene trapped(8) Radiation induced(1) Targeted(2)
Genomic Mutations involving Pfdn5 (1)
Incidental mutations (data from APF )
 
Mice homozygous for an ENU-induced mutation exhibit photoreceptor degeneration, central nervous system abnormalities, and male infertility.
 
Interactions
Pfdn5 interacts with 51 markers (Mir15a, Mir129-1, Mir129-2, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (1 records)
cDNA source data(213)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(214) cDNA(213) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000035798 (Evidence)
Ensembl Gene ModelENSMUSG00000001289 (Evidence)
Entrez Gene56612 (Evidence)
UniGene158264
DFCITC1572180, TC1643251
Consensus CDS ProjectCCDS37227.1
International Mouse Knockout Project StatusPfdn5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035798 VEGA Gene Model | MGI Sequence Detail 5758 C57BL/6J ±  kb
transcript OTTMUST00000091649 VEGA | MGI Sequence Detail 1062 Not Applicable 
polypeptide OTTMUSP00000050496 VEGA | MGI Sequence Detail 154 Not Applicable 

For the selected sequences
All sequences(60) RefSeq(3) UniProt(8)
Polymorphisms
SNPs within 2kb(70 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR009053 Prefoldin
InterPro IPR011599 Prefoldin alpha subunit
InterPro IPR004127 Prefoldin subunit
Protein Ontology PR:000012575 prefoldin subunit 5
References
(Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:203848 Abe A, et al., Prefoldin plays a role as a clearance factor in preventing proteasome inhibitor-induced protein aggregation. J Biol Chem. 2013 Sep 27;288(39):27764-76
All references(39)
Other
accession IDs
MGI:1277126, MGI:1913474, MGI:1916585

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory