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Rab2a Gene Detail
Summary
  • Symbol
    Rab2a
  • Name
    RAB2A, member RAS oncogene family
  • Synonyms
    9330148M11Rik, Rab2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928750
    NCBI Gene: 59021
  • Gene Overview
    MyGene.info: RAB2A
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:8535587-8607702 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 3.63 cM, cytoband A1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    444 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928750
protein coding gene Chr4:8535587-8607778 (.)
129S1/SvImJ MGP_129S1SvImJ_G0028039
protein coding gene Chr4:5105771-5184654 (+)
A/J MGP_AJ_G0027997
protein coding gene Chr4:5014591-5087470 (+)
AKR/J MGP_AKRJ_G0027963
protein coding gene Chr4:5043548-5122115 (+)
BALB/cJ MGP_BALBcJ_G0028009
protein coding gene Chr4:4993832-5068341 (+)
C3H/HeJ MGP_C3HHeJ_G0027739
protein coding gene Chr4:5211038-5285855 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028452
protein coding gene Chr4:5409987-5484363 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025796
protein coding gene Chr4:4708967-4782457 (+)
CAST/EiJ MGP_CASTEiJ_G0027193
protein coding gene Chr4:5052721-5131038 (+)
CBA/J MGP_CBAJ_G0027714
protein coding gene Chr4:5491810-5575730 (+)
DBA/2J MGP_DBA2J_G0027854
protein coding gene Chr4:4980450-5055515 (+)
FVB/NJ MGP_FVBNJ_G0027821
protein coding gene Chr4:4844399-4920515 (+)
LP/J MGP_LPJ_G0027965
protein coding gene Chr4:5122247-5200693 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027854
protein coding gene Chr4:5731698-5809459 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028511
protein coding gene Chr4:5041559-5115168 (+)
PWK/PhJ MGP_PWKPhJ_G0026914
protein coding gene Chr4:4976054-5048732 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026744
protein coding gene Chr4:4997611-5070246 (+)
WSB/EiJ MGP_WSBEiJ_G0027272
protein coding gene Chr4:5139295-5216146 (+)



Homology
more
  • Human Ortholog
    RAB2A, RAB2A, member RAS oncogene family
  • Vertebrate Orthologs
    9
  • Human Ortholog
    RAB2A, RAB2A, member RAS oncogene family
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LHX, RAB2
  • Links
    NCBI Gene ID: 5862
    neXtProt AC: NX_P61019
    UniProt: P61019

  • Chr Location
    8q12.1-q12.2; chr8:60516910-60623644 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 59021 NCBI Gene Model | MGI Sequence Detail 72116 C57BL/6J ±  kb
transcript NM_021518 RefSeq | MGI Sequence Detail 2057 C57BL/6  
polypeptide P53994 UniProt | EBI | MGI Sequence Detail 212 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 156
    cDNA 155
    Primer pair 1

    Microarray probesets 9
Other
Accession IDs
less
MGI:1915381, MGI:2135555
References
more
  • Summaries
    All 43
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:246195 Matsunaga K, et al., Rab2a and Rab27a cooperatively regulate the transition from granule maturation to exocytosis through the dual effector Noc2. J Cell Sci. 2017 Feb 01;130(3):541-550

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory