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Ranbp9
Gene Detail
Symbol

Name
ID
Ranbp9
RAN binding protein 9
MGI:1928741
Synonyms
IBAP-1, RanBPM
Feature Type
protein coding gene
Genetic Map
Chromosome 13
21.60 cM, cytoband A5
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr13:43402673-43480973 bp, - strand
From Ensembl annotation of GRCm38

  78301 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:38057  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RANBP9
Gene Tree: Ranbp9

Human
homologs
RANBP9, RAN binding protein 9
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 10048
neXtProt AC: NX_Q96S59

Human Synonyms: BPM90, BPM-L, RanBP7, RANBPM

Human Chr (Location): 6p23; chr6:13621498-13711580 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(13) : Gene trapped(9) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null mutation display partial neonatal lethality. Survivors display infertility with impaired spermatogenesis and oogenesis, azoospermia and premature ovarian failure.
 
Interactions
Ranbp9 interacts with 207 markers (Mir7-1, Mir9-1, Mir9-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process negative regulation of ERK1 and ERK2 cascade
Component cytoplasm, nucleus
Function enzyme binding, protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (1)    Tissues (1)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 1
cDNA source data(5)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase ranbp9 ; ZFIN ranbp9    NEW 
Molecular
reagents
All nucleic(6) cDNA(5) Primer pair(1)
Microarray probesets(5)
Other database
links
Ensembl Gene Model ENSMUSG00000038546 (Evidence)
Entrez Gene 56705 (Evidence)
NIA Mouse Gene Index U034723
Consensus CDS Project CCDS49252.1
International Mouse Phenotyping Consortium Status Ranbp9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038546 Ensembl Gene Model | MGI Sequence Detail 78301 C57BL/6J ±  kb
transcript ENSMUST00000144326 Ensembl | MGI Sequence Detail 3064 Not Applicable 
polypeptide ENSMUSP00000130636 Ensembl | MGI Sequence Detail 710 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(3) UniProt(2)
Polymorphisms
SNPs within 2kb(337 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001870 B30.2/SPRY domain
InterPro IPR013320 Concanavalin A-like lectin/glucanase domain
InterPro IPR013144 CRA domain
InterPro IPR024964 CTLH/CRA C-terminal to LisH motif domain
InterPro IPR006595 CTLH, C-terminal LisH motif
InterPro IPR006594 LIS1 homology motif
InterPro IPR003877 SPRY domain
Protein Ontology PR:000013716 ran-binding protein 9
References
(Earliest) J:71365 Nishitani H, et al., Full-sized RanBPM cDNA encodes a protein possessing a long stretch of proline and glutamine within the N-terminal region, comprising a large protein complex. Gene. 2001 Jul 11;272(1-2):25-33
(Latest) J:222184 Bao J, et al., RAN-binding protein 9 is involved in alternative splicing and is critical for male germ cell development and male fertility. PLoS Genet. 2014 Dec;10(12):e1004825
All references(35)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory