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Dnajb2
Gene Detail
 Symbol
Name
ID
Dnajb2
DnaJ (Hsp40) homolog, subfamily B, member 2
MGI:1928739
Synonyms 2700059H22Rik, Dnajb10, mDj8
Feature Type protein coding gene
Genetic Map
Chromosome 1
38.64 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:75236465-75244804 bp, + strand
From Ensembl annotation of GRCm38

  8340 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4902  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Dnajb2

Human
homologs
Human Homolog DNAJB2, DnaJ (Hsp40) homolog, subfamily B, member 2
NCBI Gene ID 3300
neXtProt AC  NX_P25686
Human Synonyms  DSMA5, HSJ1, HSJ-1, HSPF3
Human Chr (Location)  2q32-q34; chr2:219279318-219286900 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human DNAJB2
Mutations,
alleles, and
phenotypes
All mutations/alleles(9) : Gene trapped(6) Spontaneous(1) Targeted(2)
Genomic Mutations involving Dnajb2 (1)
Incidental mutations (data from Mutagenetix , APF )
Alleles Annotated to Human Diseases(1)   
Interactions
Dnajb2 interacts with 29 markers (Mir23a, Mir24-1, Mir24-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (17 annotations)
Process ER-associated ubiquitin-dependent protein catabolic process, negative regulation of cell growth, ...
Component cytosol, inclusion body, ...
Function chaperone binding, Hsp70 protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (28)    Tissues (4)    Images (17)
Theiler Stages: 23
Assay TypeResults
RNA in situ 28
cDNA source data(80)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(80) cDNA(80)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000026203 (Evidence)
Entrez Gene56812 (Evidence)
UniGene489660
DFCITC1575284, TC1594239, TC1608521, TC1691234, TC1703503
DoTSDT.101365477, DT.101394646, DT.101394647, DT.496285, DT.94275027
NIA Mouse Gene IndexU000470
Consensus CDS ProjectCCDS15068.1, CCDS35624.1
International Mouse Knockout Project StatusDnajb2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026203 Ensembl Gene Model | MGI Sequence Detail 8340 C57BL/6J ±  kb
transcript ENSMUST00000082158 Ensembl | MGI Sequence Detail 1253 Not Applicable 
polypeptide ENSMUSP00000080796 Ensembl | MGI Sequence Detail 277 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(14) UniProt(2)
Polymorphisms SNPs within 2kb(81 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001623 DnaJ domain
InterPro IPR018253 DnaJ domain, conserved site
InterPro IPR003903 Ubiquitin interacting motif
Protein Ontology PR:000029422 DnaJ homolog subfamily B member 2
References (Earliest) J:67228 Ohtsuka K, et al., Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. Cell Stress Chaperones. 2000 Apr;5(2):98-112
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(31)
Other
accession IDs
MGI:1923843

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory