About   Help   FAQ
Dnajb2 Gene Detail
Summary
  • Symbol
    Dnajb2
  • Name
    DnaJ heat shock protein family (Hsp40) member B2
  • Synonyms
    2700059H22Rik, Dnajb10, mDj8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928739
    NCBI Gene: 56812
  • Gene Overview
    MyGene.info: DNAJB2
  • Alliance
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:75236406-75245692 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 38.64 cM, cytoband C3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    85 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928739
protein coding gene Chr1:75236403-75245692 (.)
129S1/SvImJ MGP_129S1SvImJ_G0016181
protein coding gene Chr1:75800499-75809769 (+)
A/J MGP_AJ_G0016164
protein coding gene Chr1:73159116-73168417 (+)
AKR/J MGP_AKRJ_G0016121
protein coding gene Chr1:75188284-75197564 (+)
BALB/cJ MGP_BALBcJ_G0016119
protein coding gene Chr1:73220046-73229137 (+)
C3H/HeJ MGP_C3HHeJ_G0015950
protein coding gene Chr1:75521501-75531373 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016572
protein coding gene Chr1:78749584-78758891 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014293
protein coding gene Chr1:68719556-68729474 (+)
CAST/EiJ MGP_CASTEiJ_G0015534
protein coding gene Chr1:74862062-74873114 (+)
CBA/J MGP_CBAJ_G0015923
protein coding gene Chr1:81309989-81319104 (+)
DBA/2J MGP_DBA2J_G0016024
protein coding gene Chr1:72477339-72486428 (+)
FVB/NJ MGP_FVBNJ_G0016027
protein coding gene Chr1:71676633-71687429 (+)
LP/J MGP_LPJ_G0016096
protein coding gene Chr1:76924756-76934041 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016047
protein coding gene Chr1:84667879-84677134 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016619
protein coding gene Chr1:75259271-75268556 (+)
PWK/PhJ MGP_PWKPhJ_G0015321
protein coding gene Chr1:71948813-71958209 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015099
protein coding gene Chr1:74621775-74630978 (+)
WSB/EiJ MGP_WSBEiJ_G0015596
protein coding gene Chr1:75071169-75080444 (+)



Homology
more
  • Human Ortholog
    DNAJB2, DnaJ heat shock protein family (Hsp40) member B2
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DNAJB2, DnaJ heat shock protein family (Hsp40) member B2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CMT2T, DSMA5, HSJ1, HSJ-1, HSPF3
  • Links
    NCBI Gene ID: 3300
    neXtProt AC: NX_P25686
    UniProt: P25686

  • Chr Location
    2q35; chr2:219279318-219286900 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 4902
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DNAJB2
  • Gene Tree
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotype references
  • All Mutations and Alleles
    13
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    6
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    4 involving Dnajb2
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000026203 Ensembl Gene Model | MGI Sequence Detail 9287 C57BL/6J ±  kb
transcript ENSMUST00000188931 Ensembl | MGI Sequence Detail 3066 Not Applicable  
polypeptide ENSMUSP00000140566 Ensembl | MGI Sequence Detail 324 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 81
    cDNA 81

    Microarray probesets 4
Other
Accession IDs
less
MGI:1923843
References
more
  • Summaries
    All 50
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 4
    Phenotypes 22
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory