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Baalc Gene Detail
Summary
  • Symbol
    Baalc
  • Name
    brain and acute leukemia, cytoplasmic
  • Synonyms
    2810457D07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928704
    NCBI Gene: 118452
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr15:38933909-38952917 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 15, 15.18 cM, cytoband C
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    268 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928704
protein coding gene Chr15:38933144-38952917 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021810
protein coding gene Chr15:37344823-37364539 (+)
A/J MGP_AJ_G0021770
protein coding gene Chr15:35888384-35907938 (+)
AKR/J MGP_AKRJ_G0021751
protein coding gene Chr15:36966300-36984951 (+)
BALB/cJ MGP_BALBcJ_G0021777
protein coding gene Chr15:35936422-35953631 (+)
C3H/HeJ MGP_C3HHeJ_G0021551
protein coding gene Chr15:36903332-36922504 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022216
protein coding gene Chr15:38778047-38796475 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019753
protein coding gene Chr15:33658283-33673448 (+)
CAST/EiJ MGP_CASTEiJ_G0021068
protein coding gene Chr15:37340478-37359298 (+)
CBA/J MGP_CBAJ_G0021520
protein coding gene Chr15:40116058-40138691 (+)
DBA/2J MGP_DBA2J_G0021644
protein coding gene Chr15:35725843-35744062 (+)
FVB/NJ MGP_FVBNJ_G0021622
protein coding gene Chr15:35138727-35155126 (+)
LP/J MGP_LPJ_G0021714
protein coding gene Chr15:37209309-37228275 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021646
protein coding gene Chr15:43002464-43020674 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022239
protein coding gene Chr15:37100802-37121744 (+)
PWK/PhJ MGP_PWKPhJ_G0020813
protein coding gene Chr15:35791597-35807523 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020650
protein coding gene Chr15:36793645-36814410 (+)
WSB/EiJ MGP_WSBEiJ_G0021123
protein coding gene Chr15:37048914-37065043 (+)



Homology
more
  • Human Ortholog
    BAALC, BAALC binder of MAP3K1 and KLF4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    BAALC, BAALC binder of MAP3K1 and KLF4
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 79870
    neXtProt AC: NX_Q8WXS3
    UniProt: Q8WXS3

  • Chr Location
    8q22.3; chr8:103140693-103230305 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
  • UniGene
Representative SequencesLengthStrain/SpeciesFlank
genomic 118452 NCBI Gene Model | MGI Sequence Detail 19009 C57BL/6J ±  kb
transcript NM_080640 RefSeq | MGI Sequence Detail 4177 C57BL/6  
polypeptide Q8VHV1 UniProt | EBI | MGI Sequence Detail 145 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR009728 BAALC
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 8
Other
Accession IDs
less
MGI:1920029
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:260290 Eisfeld AK, et al., Intronic miR-3151 within BAALC drives leukemogenesis by deregulating the TP53 pathway. Sci Signal. 2014 Apr 15;7(321):ra36

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory