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Gpr37l1
Gene Detail
Symbol

Name
ID
Gpr37l1
G protein-coupled receptor 37-like 1
MGI:1928503
Synonyms
CAG-18, D0Kist8
Feature Type
protein coding gene
Genetic Map
Chromosome 1
58.25 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:135160234-135167681 bp, - strand
From VEGA annotation of GRCm38

  7448 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:3500  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GPR37L1
Protein SuperFamily: endothelin B receptor-like protein
Gene Tree: Gpr37l1

Human
homologs
GPR37L1, G protein-coupled receptor 37 like 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 9283
neXtProt AC: NX_O60883

Human Synonyms: ET(B)R-LP-2, ETBR-LP-2

Human Chr (Location): 1q32.1; chr1:202118705-202131425 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(7) : Gene trapped(2) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for one knock-out allele of this gene displayed a normal phenotype. Mice homozygous for another knock-out allele exhibit precocious cerebellum development and improved motor functions.
 
Interactions
Gpr37l1 interacts with 99 markers (Mir7-1, Mir7-2, Mir7b, ...)
Expression
Literature Summary: (3 records)
Data Summary: Results (24)    Tissues (15)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 24
cDNA source data(11)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase gpr37l1    NEW 
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000022102 (Evidence)
Ensembl Gene Model ENSMUSG00000026424 (Evidence)
Entrez Gene 171469 (Evidence)
UniGene 272290
DFCI TC1582324
DoTS DT.50316912
NIA Mouse Gene Index U021792
Consensus CDS Project CCDS48371.1
International Mouse Phenotyping Consortium Status Gpr37l1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022102 VEGA Gene Model | MGI Sequence Detail 7448 C57BL/6J ±  kb
transcript OTTMUST00000052472 VEGA | MGI Sequence Detail 2269 Not Applicable 
polypeptide OTTMUSP00000024885 VEGA | MGI Sequence Detail 481 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(2)
Polymorphisms
SNPs within 2kb(108 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017452 GPCR, rhodopsin-like, 7TM
InterPro IPR003909 G protein-coupled receptor 37 orphan
InterPro IPR000276 G protein-coupled receptor, rhodopsin-like
Protein Ontology PR:000001112 prosaposin receptor GPR37L1
References
(Earliest) J:44212 Kim SJ, et al., Cloning of novel trinucleotide-repeat (CAG) containing genes in mouse brain. Biochem Biophys Res Commun. 1997 Nov 7;240(1):239-43
(Latest) J:220996 La Sala G, et al., Modulation of Dhh signaling and altered Sertoli cell function in mice lacking the GPR37-prosaposin receptor. FASEB J. 2015 May;29(5):2059-69
All references(40)
Other
accession IDs
MGD-MRK-37477, MGI:108433, MGI:2138545

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/25/2015
MGI 6.0
The Jackson Laboratory