Nudt3 Gene Detail

Summary

• Symbol
  Nudt3
• Name
  nudix (nucleotide diphosphate linked moiety X)-type motif 3
• Synonyms
  1110011B09Rik, diphosphoinositol polyphosphate phosphohydrolase, Dipp

• Feature Type
  protein coding gene
• IDs
  MGI:1928484
  NCBI Gene: 56409
• Gene Overview
  MyGene.info: NUDT3

Location & Maps

• Sequence Map
  Chr17:27579382-27623465 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    44084 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, 14.59 cM
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  NUDT3, nudix hydrolase 3

• Vertebrate Orthologs
  8

• Human Ortholog
  NUDT3, nudix hydrolase 3
  Orthology source: HomoloGene, HGNC
• Synonyms
  DIPP, DIPP1, DIPP-1
• Links
  HGNC:8050

  NCBI Gene ID: 11165

  neXtProt AC: NX_O95989

  UniProt: O95989

  
  
• Chr Location
  6p21.31; chr6:34287194-34392680 (-)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 31400
  1 human;1 mouse;1 rat;1 cattle;1 dog;1 chicken;1 zebrafish;1 macaque, rhesus
  
• HCOP
  human homology predictions: NUDT3
• Gene Tree
  Nudt3
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  10 phenotype references
  

• All Mutations and Alleles
  61
• Gene trapped
  58
• Radiation induced
  1
• Targeted
  2
• Genomic Mutations
  1 involving Nudt3
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  50 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  16
• GO References
  2

• External Resources
  FuncBase

Expression

• cDNA Data
  4

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  ZFIN nudt3a, nudt3b

Interactions

• Nudt3 interacts with 137 markers (Mir9-1, Mir9-2, Mir9-3, ...) View All

Sequences &
Gene Models

• All Sequences
  48
• RefSeq
  4
• CCDS
  CCDS28566.1, CCDS70776.1

• VEGA
  OTTMUSG00000018655 (Evidence)
• Ensembl
  ENSMUSG00000024213 (Evidence)
• NCBI Gene
  56409 (Evidence)

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000018655	VEGA Gene Model | MGI Sequence Detail	44084	C57BL/6J
transcript	OTTMUST00000044911	VEGA | MGI Sequence Detail	2193	Not Applicable
polypeptide	OTTMUSP00000020186	VEGA | MGI Sequence Detail	168	Not Applicable

Polymorphisms

• SNPs within 2kb
  543 from dbSNP Build 142

Protein
Information

• Protein Ontology
  PR:000011494 diphosphoinositol polyphosphate phosphohydrolase 1
  (term hierarchy)

Molecular
Reagents

• All nucleic 4

  cDNA 4

  
  

  Microarray probesets 3

Other
Accession IDs

MGI:1915745, MGI:2146786

References

• Summaries
  All 31

  Gene Ontology 2

  Phenotypes 10
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:194116 Flachs P, et al., Interallelic and intergenic incompatibilities of the Prdm9 (Hst1) gene in mouse hybrid sterility. PLoS Genet. 2012;8(11):e1003044