About   Help   FAQ
Stx5a Gene Detail
Summary
  • Symbol
    Stx5a
  • Name
    syntaxin 5A
  • Synonyms
    0610031F24Rik, D19Ertd627e, syntaxin 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928483
    NCBI Gene: 56389
  • Gene Overview
    MyGene.info: STX5
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:8741424-8755642 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 5.45 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    38 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928483
protein coding gene Chr19:8741413-8756069 (.)
129S1/SvImJ MGP_129S1SvImJ_G0024806
protein coding gene Chr19:6013413-6029389 (+)
A/J MGP_AJ_G0024774
protein coding gene Chr19:5693391-5708049 (+)
AKR/J MGP_AKRJ_G0024749
protein coding gene Chr19:5781722-5796376 (+)
BALB/cJ MGP_BALBcJ_G0024774
protein coding gene Chr19:5796161-5812278 (+)
C3H/HeJ MGP_C3HHeJ_G0024540
protein coding gene Chr19:5862533-5877226 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025221
protein coding gene Chr19:6132929-6147877 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022650
protein coding gene Chr19:5934669-5951302 (+)
CAST/EiJ MGP_CASTEiJ_G0024013
protein coding gene Chr19:5509780-5525228 (+)
CBA/J MGP_CBAJ_G0024514
protein coding gene Chr19:6248229-6269144 (+)
DBA/2J MGP_DBA2J_G0024641
protein coding gene Chr19:5523629-5538686 (+)
FVB/NJ MGP_FVBNJ_G0024608
protein coding gene Chr19:5599274-5613487 (+)
LP/J MGP_LPJ_G0024728
protein coding gene Chr19:5901806-5918532 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024635
protein coding gene Chr19:6118378-6133181 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025270
protein coding gene Chr19:5826532-5840755 (+)
PWK/PhJ MGP_PWKPhJ_G0023758
protein coding gene Chr19:5188938-5203887 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023563
protein coding gene Chr19:5423532-5440222 (+)
WSB/EiJ MGP_WSBEiJ_G0024075
protein coding gene Chr19:5790856-5807799 (+)



Homology
more
  • Human Ortholog
    STX5, syntaxin 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    STX5, syntaxin 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    SED5, STX5A
  • Links
    NCBI Gene ID: 6811
    neXtProt AC: NX_Q13190
    UniProt: Q13190

  • Chr Location
    11q12.3; chr11:62806860-62832091 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 2381
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: STX5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56389 NCBI Gene Model | MGI Sequence Detail 14219 C57BL/6J ±  kb
transcript NM_019829 RefSeq | MGI Sequence Detail 2128 C57BL/6  
polypeptide Q8K1E0 UniProt | EBI | MGI Sequence Detail 355 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    10 Sequences
  • InterPro Domains
    IPR010989 SNARE
    IPR021538 Syntaxin-5, N-terminal, Sly1p-binding domain
    IPR006012 Syntaxin/epimorphin, conserved site
    IPR000727 Target SNARE coiled-coil homology domain
Molecular
Reagents
less
  • All nucleic 145
    cDNA 144
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1277164, MGI:1917590
References
more
  • Summaries
    All 44
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:46012 Hay JC, et al., Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. Cell. 1997 Apr 4;89(1):149-58
  • Latest
    J:253982 Norlin S, et al., The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival. Development. 2018 Jan 3;145(1)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory