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Stx5a Gene Detail
Summary
  • Symbol
    Stx5a
  • Name
    syntaxin 5A
  • Synonyms
    0610031F24Rik, D19Ertd627e, syntaxin 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928483
    NCBI Gene: 56389
  • Gene Overview
    MyGene.info: STX5
Location & Maps
more
  • Sequence Map
    Chr19:8741413-8756069 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      14657 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 19, 5.45 cM
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    4 experiments
Homology
more
  • Human Ortholog
    STX5, syntaxin 5
  • Vertebrate Orthologs
    10
  • Human Ortholog
    STX5, syntaxin 5
    Orthology source: HGNC, HomoloGene
  • Synonyms
    SED5, STX5A
  • Links
    NCBI Gene ID: 6811
    neXtProt AC: NX_Q13190

  • Chr Location
    11q12.3; chr11:62806860-62832091 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 2381
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 western clawed frog;2 zebrafish
  • HCOP
    human homology predictions: STX5
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    11
  • Gene trapped
    8
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000039850 VEGA Gene Model | MGI Sequence Detail 14657 C57BL/6J ±  kb
transcript OTTMUST00000103607 VEGA | MGI Sequence Detail 1780 Not Applicable  
polypeptide OTTMUSP00000057907 VEGA | MGI Sequence Detail 442 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    38 from dbSNP Build 142
Protein
Information
less
  • UniProt
    10 Sequences
  • InterPro Domains
    IPR021538 Syntaxin-5, N-terminal, Sly1p-binding domain
    IPR006012 Syntaxin/epimorphin, conserved site
    IPR000727 Target SNARE coiled-coil homology domain
    IPR010989 t-SNARE
Molecular
Reagents
less
  • All nucleic 143
    cDNA 142
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1277164, MGI:1917590
References
more
  • Summaries
    All 39
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:46012 Hay JC, et al., Protein interactions regulating vesicle transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells. Cell. 1997 Apr 4;89(1):149-58
  • Latest
    J:170300 Chen J, et al., Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition. Genes Dev. 2011 Apr 1;25(7):755-66

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/24/2016
MGI 6.04
The Jackson Laboratory