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Trip4 Gene Detail
Summary
  • Symbol
    Trip4
  • Name
    thyroid hormone receptor interactor 4
  • Synonyms
    4930558E03Rik, ASC-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928469
    NCBI Gene: 56404
  • Gene Overview
    MyGene.info: TRIP4
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:65828930-65908794 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 35.55 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    225 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928469
protein coding gene Chr9:65828926-65908810 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034967
protein coding gene Chr9:65626756-65707781 (-)
A/J MGP_AJ_G0034947
protein coding gene Chr9:63380678-63462396 (-)
AKR/J MGP_AKRJ_G0034877
protein coding gene Chr9:64898386-64975752 (-)
BALB/cJ MGP_BALBcJ_G0034940
protein coding gene Chr9:63096898-63178049 (-)
C3H/HeJ MGP_C3HHeJ_G0034650
protein coding gene Chr9:65420790-65503739 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035459
protein coding gene Chr9:67392633-67486864 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032370
protein coding gene Chr9:63026927-63110149 (-)
CAST/EiJ MGP_CASTEiJ_G0033971
protein coding gene Chr9:65601795-65694378 (-)
CBA/J MGP_CBAJ_G0034621
protein coding gene Chr9:69750933-69842335 (-)
DBA/2J MGP_DBA2J_G0034780
protein coding gene Chr9:63151432-63235167 (-)
FVB/NJ MGP_FVBNJ_G0034722
protein coding gene Chr9:62493535-62571619 (-)
LP/J MGP_LPJ_G0034863
protein coding gene Chr9:65866113-65947401 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034764
protein coding gene Chr9:70994389-71093519 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035481
protein coding gene Chr9:64992930-65086280 (-)
PWK/PhJ MGP_PWKPhJ_G0033675
protein coding gene Chr9:63351947-63434227 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033509
protein coding gene Chr9:65280148-65358687 (-)
WSB/EiJ MGP_WSBEiJ_G0034084
protein coding gene Chr9:64888682-64974486 (-)



Homology
more
  • Human Ortholog
    TRIP4, thyroid hormone receptor interactor 4
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TRIP4, thyroid hormone receptor interactor 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ASC1, ASC-1, HsT17391, MDCDC, SMABF1, ZC2HC5
  • Links
    NCBI Gene ID: 9325
    neXtProt AC: NX_Q15650
    UniProt: Q15650

  • Chr Location
    15q22.31; chr15:64387804-64455303 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032386 Ensembl Gene Model | MGI Sequence Detail 79865 C57BL/6J ±  kb
transcript ENSMUST00000119245 Ensembl | MGI Sequence Detail 4211 Not Applicable  
polypeptide ENSMUSP00000112385 Ensembl | MGI Sequence Detail 581 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 7
Other
Accession IDs
less
MGI:1922616, MGI:2143370
References
more
  • Summaries
    All 39
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:232493 Davignon L, et al., The transcription coactivator ASC-1 is a regulator of skeletal myogenesis, and its deficiency causes a novel form of congenital muscle disease. Hum Mol Genet. 2016 Apr 15;25(8):1559-73

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory