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Snx1
Gene Detail
 Symbol
Name
ID
Snx1
sorting nexin 1
MGI:1928395
Feature Type protein coding gene
Genetic Map
Chromosome 9
35.71 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr9:66088133-66126587 bp, - strand
From VEGA annotation of GRCm38

  38455 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:99716  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: sorting nexin, Snx1 type
Gene Tree: Snx1

Human
homologs
Human Homolog SNX1, sorting nexin 1
NCBI Gene ID 6642
neXtProt AC  NX_Q13596
Human Synonyms  HsT17379, VPS5
Human Chr (Location)  15q22.31; chr15:64094076-64144234 (+)  GRCh38
Alleles
and
phenotypes
All alleles(12) : Gene trapped(10) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutant mice are viable and fertile and do not exhibit any apparent abnormalities.
 
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process early endosome to Golgi transport, intracellular protein transport, ...
Component cytoplasm, cytoplasmic membrane-bounded vesicle, ...
Function lipid binding, phosphatidylinositol binding
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (2)    Tissues (2)    Images (1)
Theiler Stages: 13
Assay TypeResults
RT-PCR 2
cDNA source data(156)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(157) cDNA(156) Primer pair(1)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000031789 (Evidence)
Ensembl Gene ModelENSMUSG00000032382 (Evidence)
Entrez Gene56440 (Evidence)
UniGene271891
DFCITC1573360, TC1772607
DoTSDT.101352285, DT.535366
NIA Mouse Gene IndexU031018
Consensus CDS ProjectCCDS52839.1
International Mouse Knockout Project StatusSnx1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031789 VEGA Gene Model | MGI Sequence Detail 38455 C57BL/6J ±  kb
transcript OTTMUST00000078780 VEGA | MGI Sequence Detail 2073 Not Applicable 
polypeptide OTTMUSP00000041926 VEGA | MGI Sequence Detail 521 Not Applicable 

For the selected sequences
All sequences(67) RefSeq(2) UniProt(6)
Polymorphisms SNPs within 2kb(224 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001683 Phox homologous domain
InterPro IPR005329 Sorting nexin, N-terminal
InterPro IPR015404 Vps5 C-terminal
Protein Ontology PR:000015358 sorting nexin-1
References (Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:193740 Villar VA, et al., Sorting nexin 1 loss results in D5 dopamine receptor dysfunction in human renal proximal tubule cells and hypertension in mice. J Biol Chem. 2013 Jan 4;288(1):152-63
All references(41)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory