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Dpt
Gene Detail
Symbol

Name
ID
Dpt
dermatopontin
MGI:1928392
Synonyms
1810032B19Rik, 5033416F05Rik, early quiescence protein-1, EQ-1
Feature Type
protein coding gene
Genetic Map
Chromosome 1
72.12 cM, cytoband H2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:164796644-164824266 bp, + strand
From VEGA annotation of GRCm38

  27623 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:1458  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: DPT
Gene Tree: Dpt

Human
homologs
DPT, dermatopontin
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 1805
neXtProt AC: NX_Q07507

Human Synonyms: TRAMP

Human Chr (Location): 1q12-q23; chr1:168695457-168729204 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Targeted(2)
Incidental mutations (data from APF , CvDC )
 
Homozygotes for a targeted null mutation exhibit skin with increased elasticity, decreased thickness, and reduced collagen content, and possess more subcutaneous adipose tissue. Corneal thickness is reduced as well.
 
Interactions
Dpt interacts with 153 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell adhesion, collagen fibril organization, ...
Component extracellular exosome, extracellular matrix, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (109)    Tissues (13)    Images (24)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 109
cDNA source data(74)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase dpt ; ZFIN dpt    NEW 
Molecular
reagents
All nucleic(74) cDNA(74)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000049869 (Evidence)
Ensembl Gene Model ENSMUSG00000026574 (Evidence)
Entrez Gene 56429 (Evidence)
UniGene 28935
DFCI TC1580976, TC1676087
DoTS DT.494746
NIA Mouse Gene Index U001026
Consensus CDS Project CCDS15437.1
International Mouse Phenotyping Consortium Status Dpt
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000049869 VEGA Gene Model | MGI Sequence Detail 27623 C57BL/6J ±  kb
transcript OTTMUST00000126982 VEGA | MGI Sequence Detail 1724 Not Applicable 
polypeptide OTTMUSP00000068621 VEGA | MGI Sequence Detail 201 Not Applicable 

For the selected sequences
All sequences(19) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(481 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026645 Dermatopontin family
Protein Ontology PR:000006670 dermatopontin
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:214811 Weiss AC, et al., Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme. Development. 2014 Sep;141(17):3420-30
All references(35)
Other
accession IDs
MGI:1921422, MGI:1925481

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory