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B4galt6 Gene Detail
Summary
  • Symbol
    B4galt6
  • Name
    UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928380
    NCBI Gene: 56386
Location & Maps
more
  • Sequence Map
    Chr18:20684599-20746404 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      61806 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 11.48 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    B4GALT6, beta-1,4-galactosyltransferase 6
  • Vertebrate Orthologs
    10
  • Human Ortholog
    B4GALT6, beta-1,4-galactosyltransferase 6
    Orthology source: HGNC, HomoloGene
  • Synonyms
    B4Gal-T6, beta4Gal-T6
  • Links
    NCBI Gene ID: 9331
    neXtProt AC: NX_Q9UBX8

  • Chr Location
    18q11; chr18:31622246-31725286 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Mice homozygous for disruptions in this gene display a normal phenotype.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 56386 NCBI Gene Model | MGI Sequence Detail 61806 C57BL/6J ±  kb
transcript NM_019737 RefSeq | MGI Sequence Detail 5808 C57BL/6  
polypeptide Q9WVK5 UniProt | EBI | MGI Sequence Detail 382 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    361 from dbSNP Build 142
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000004610 beta-1,4-galactosyltransferase 6
  • EC
  • InterPro Domains
    IPR003859 Beta-1,4-galactosyltransferase
    IPR027791 Galactosyltransferase, C-terminal
    IPR027995 Galactosyltransferase, N-terminal
    IPR029044 Nucleotide-diphospho-sugar transferases
Molecular
Reagents
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  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
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MGI:2147179, MGI:2147314
References
more
  • Summaries
    All 36
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:47946 Nomura T, et al., Purification, cDNA cloning, and expression of UDP-Gal: glucosylceramide beta-1,4-galactosyltransferase from rat brain. J Biol Chem. 1998 May 29;273(22):13570-7
  • Latest
    J:227742 Mayo L, et al., Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation. Nat Med. 2014 Oct;20(10):1147-56

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory