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Dnajc7 Gene Detail
Summary
  • Symbol
    Dnajc7
  • Name
    DnaJ heat shock protein family (Hsp40) member C7
  • Synonyms
    2010003F24Rik, 2010004G07Rik, mDj11, mTpr2, Ttc2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928373
    NCBI Gene: 56354
  • Gene Overview
    MyGene.info: DNAJC7
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:100582818-100620168 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 63.47 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    240 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928373
protein coding gene Chr11:100582818-100620168 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019161
protein coding gene Chr11:103345530-103386824 (-)
A/J MGP_AJ_G0019129
protein coding gene Chr11:99034401-99071537 (-)
AKR/J MGP_AKRJ_G0019098
protein coding gene Chr11:102094985-102136817 (-)
BALB/cJ MGP_BALBcJ_G0019103
protein coding gene Chr11:99518204-99555878 (-)
C3H/HeJ MGP_C3HHeJ_G0018912
protein coding gene Chr11:102282071-102319699 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019552
protein coding gene Chr11:106562303-106600691 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017178
protein coding gene Chr11:96453191-96491962 (-)
CAST/EiJ MGP_CASTEiJ_G0018466
protein coding gene Chr11:103257908-103298316 (-)
CBA/J MGP_CBAJ_G0018881
protein coding gene Chr11:110993680-111038527 (-)
DBA/2J MGP_DBA2J_G0018993
protein coding gene Chr11:98571004-98608346 (-)
FVB/NJ MGP_FVBNJ_G0018983
protein coding gene Chr11:98107017-98144496 (-)
LP/J MGP_LPJ_G0019062
protein coding gene Chr11:103908231-103948468 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019014
protein coding gene Chr11:110596524-110639228 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019590
protein coding gene Chr11:102429162-102468095 (-)
PWK/PhJ MGP_PWKPhJ_G0018229
protein coding gene Chr11:99610994-99649477 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018021
protein coding gene Chr11:102163989-102208027 (-)
WSB/EiJ MGP_WSBEiJ_G0018515
protein coding gene Chr11:102412377-102451893 (-)



Homology
more
  • Human Ortholog
    DNAJC7, DnaJ heat shock protein family (Hsp40) member C7
  • Vertebrate Orthologs
    11
  • Human Ortholog
    DNAJC7, DnaJ heat shock protein family (Hsp40) member C7
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DJ11, DJC7, TPR2, TTC2
  • Links
    NCBI Gene ID: 7266
    neXtProt AC: NX_Q99615
    UniProt: Q99615

  • Chr Location
    17q21.2; chr17:41976421-42021371 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 68306
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DNAJC7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    1 images
    22 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Male mice homozygous for a knock-out allele exhibit hepatic steatosis and increased serum cholesterol.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 56354 NCBI Gene Model | MGI Sequence Detail 37351 C57BL/6J ±  kb
transcript NM_019795 RefSeq | MGI Sequence Detail 2312 C57BL/6  
polypeptide Q9QYI3 UniProt | EBI | MGI Sequence Detail 494 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 167
    cDNA 167

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913794, MGI:1914883
References
more
  • Summaries
    All 50
    Gene Ontology 2
    Phenotypes 22
  • Earliest
    J:50799 Liu P, et al., Embryonic lethality and tumorigenesis caused by segmental aneuploidy on mouse chromosome 11. Genetics. 1998 Nov;150(3):1155-68
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory