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Rhog
Gene Detail
Symbol

Name
ID
Rhog
ras homolog gene family, member G
MGI:1928370
Synonyms
2810426G09Rik, Arhg, RhoG, Sid10750
Feature Type
protein coding gene
Genetic Map
Chromosome 7
54.71 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:102239123-102250123 bp, - strand
From VEGA annotation of GRCm38

  11001 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68196  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: small GTPase, Rho type
Gene Tree: Rhog

Human
homologs
Human Homolog RHOG, ras homolog family member G
NCBI Gene ID 391
neXtProt AC  NX_P84095
Human Synonyms  ARHG
Human Chr (Location)  11p15.5-p15.4; chr11:3826978-3840983 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(5) Targeted(3)
 
Mice homozygous for disruptions in this gene display and essentially normal phenotype.
 
Interactions
Rhog interacts with 124 markers (Mir1a-1, Mir1a-2, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process actin cytoskeleton organization, activation of Rac GTPase activity, ...
Component extracellular vesicular exosome, focal adhesion, ...
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(58)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(58) cDNA(58)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000022529 (Evidence)
Ensembl Gene ModelENSMUSG00000073982 (Evidence)
Entrez Gene56212 (Evidence)
UniGene259795
DFCITC1688826, TC1577668
NIA Mouse Gene IndexU028940
Consensus CDS ProjectCCDS21529.1
International Mouse Knockout Project StatusRhog
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022529 VEGA Gene Model | MGI Sequence Detail 11001 C57BL/6J ±  kb
transcript OTTMUST00000053958 VEGA | MGI Sequence Detail 1269 Not Applicable 
polypeptide OTTMUSP00000025699 VEGA | MGI Sequence Detail 191 Not Applicable 

For the selected sequences
All sequences(30) RefSeq(2) UniProt(5)
Polymorphisms
SNPs within 2kb(189 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003578 Small GTPase superfamily, Rho type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013981 rho-related GTP-binding protein RhoG
References
(Earliest) J:4309 Miki T, et al., Oncogene ect2 is related to regulators of small GTP-binding proteins [published erratum appears in Nature 1993 Aug 19;364(6439):737]. Nature. 1993 Apr 1;362(6419):462-5
(Latest) J:204983 Kim S, et al., RhoG protein regulates glycoprotein VI-Fc receptor gamma-chain complex-mediated platelet activation and thrombus formation. J Biol Chem. 2013 Nov 22;288(47):34230-8
All references(48)
Other
accession IDs
MGI:1920001

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory