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Rhog
Gene Detail
Symbol

Name
ID
Rhog
ras homolog gene family, member G
MGI:1928370
Synonyms
2810426G09Rik, Arhg, RhoG, Sid10750
Feature Type
protein coding gene
Genetic Map
Chromosome 7
54.71 cM, cytoband F1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:102239123-102250123 bp, - strand
From VEGA annotation of GRCm38

  11001 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:68196  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: RHOG
Protein SuperFamily: small GTPase, Rho type
Gene Tree: Rhog

Human
homologs
RHOG, ras homolog family member G
Orthology source: HomoloGene, HGNC

IDs:
NCBI Gene ID: 391
neXtProt AC: NX_P84095

Human Synonyms: ARHG

Human Chr (Location): 11p15.5-p15.4; chr11:3826978-3840983 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(8) : Gene trapped(5) Targeted(3)
 
Mice homozygous for disruptions in this gene display and essentially normal phenotype.
 
Interactions
Rhog interacts with 124 markers (Mir1a-1, Mir1a-2, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process actin cytoskeleton organization, activation of GTPase activity, ...
Component extracellular exosome, focal adhesion, ...
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
cDNA source data(58)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase rhog ; ZFIN rhogb    NEW 
Molecular
reagents
All nucleic(58) cDNA(58)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000022529 (Evidence)
Ensembl Gene Model ENSMUSG00000073982 (Evidence)
Entrez Gene 56212 (Evidence)
UniGene 259795
DFCI TC1688826, TC1577668
NIA Mouse Gene Index U028940
Consensus CDS Project CCDS21529.1
International Mouse Phenotyping Consortium Status Rhog
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022529 VEGA Gene Model | MGI Sequence Detail 11001 C57BL/6J ±  kb
transcript OTTMUST00000053958 VEGA | MGI Sequence Detail 1269 Not Applicable 
polypeptide OTTMUSP00000025699 VEGA | MGI Sequence Detail 191 Not Applicable 

For the selected sequences
All sequences(28) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(189 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR003578 Small GTPase superfamily, Rho type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013981 rho-related GTP-binding protein RhoG
References
(Earliest) J:4309 Miki T, et al., Oncogene ect2 is related to regulators of small GTP-binding proteins [published erratum appears in Nature 1993 Aug 19;364(6439):737]. Nature. 1993 Apr 1;362(6419):462-5
(Latest) J:214692 Damoulakis G, et al., P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils. J Cell Sci. 2014 Jun 1;127(Pt 11):2589-600
All references(47)
Other
accession IDs
MGI:1920001

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory