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Nmi Gene Detail
Summary
  • Symbol
    Nmi
  • Name
    N-myc (and STAT) interactor
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928368
    NCBI Gene: 64685
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:51838517-51863241 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 29.98 cM, cytoband C1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    838 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1928368
 protein coding gene Chr2:51838499-51863506 (-)
129S1/SvImJ ENSMUSG00200010758
 protein coding gene Chr2:48815657-48828015 (-)
A/J ENSMUSG00195010060
 protein coding gene Chr2:48964696-48977056 (-)
AKR/J ENSMUSG00220019959
 protein coding gene Chr2:49097680-49110037 (-)
BALB/cJ ENSMUSG00180020621
 protein coding gene Chr2:48959198-48971372 (-)
C3H/HeJ ENSMUSG00175013219
 protein coding gene Chr2:48988914-49001289 (-)
C57BL/6NJ ENSMUSG00215010077
 protein coding gene Chr2:49004968-49017142 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023553
 protein coding gene Chr2:47266016-47290934 (-)
CAST/EiJ ENSTCUG00005001486
 protein coding gene Chr2:48505269-48517597 (-)
CBA/J ENSMUSG00210000559
 protein coding gene Chr2:49002113-49014472 (-)
DBA/2J ENSMUSG00185002580
 protein coding gene Chr2:48869588-48881944 (-)
FVB/NJ ENSMUSG00205001523
 protein coding gene Chr2:48674378-48686710 (-)
JF1/MsJ ENSUMUG00000000426
 protein coding gene Chr2:48698368-48710565 (-)
LP/J ENSMUSG00230000560
 protein coding gene Chr2:50783812-50795985 (-)
NOD/ShiLtJ ENSMUSG00190001884
 protein coding gene Chr2:48917288-48929655 (-)
NZO/HlLtJ ENSMUSG00225000275
 protein coding gene Chr2:58494925-58507098 (-)
PWK/PhJ ENSLUMG00010004141
 protein coding gene Chr2:48854047-48866346 (-)
SPRET/EiJ ENSMSPG00010010572
 protein coding gene Chr2:49840965-49853333 (-)
WSB/EiJ ENSIUOG00005001181
 protein coding gene Chr2:48955195-48967554 (-)



Homology
more
  • Human Ortholog
    NMI, N-myc and STAT interactor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NMI, N-myc and STAT interactor
  • Links
    NCBI Gene ID: 9111
    UniProt: Q13287

  • Chr Location
    2q23.3; chr2:151270467-151289908 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 3 alleles in 3 genetic backgrounds
    2 phenotypes from multigenic genotypes
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Conditional knockout in mammary epithelium alters mammary development and increases the aggressiveness and metastatic potential of induced mammary tumors. Mice homozygous for a different null allele exhibit reduced susceptibility to LPS treatment.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    58
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    695
  • Tissues
    97
  • cDNA Data
    37
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 64685 NCBI Gene Model | MGI Sequence Detail 24725 C57BL/6J ±  kb
    transcript NM_001421887 RefSeq | MGI Sequence Detail 1318 C57BL/6  
    polypeptide O35309 UniProt | EBI | MGI Sequence Detail 314 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 38
      cDNA 37
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 47
      Developmental Gene Expression 3
      Gene Ontology 10
      Phenotypes 14
    • Earliest
      J:385656 Zhu M, et al., Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling. Cell. 1999 Jan 8;96(1):121-30
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory