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Nisch Gene Detail
Summary
  • Symbol
    Nisch
  • Name
    nischarin
  • Synonyms
    1200007D05Rik, 3202002H23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928323
    NCBI Gene: 64652
  • Gene Overview
    MyGene.info: NISCH
Location & Maps
more
  • Sequence Map
    Chr14:31170930-31216946 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      46017 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    NISCH, nischarin
  • Vertebrate Orthologs
    4
  • Human Ortholog
    NISCH, nischarin
    Orthology source: HGNC
  • Synonyms
    hIRAS, I-1, IR1, IRAS
  • Links
    NCBI Gene ID: 11188
    neXtProt AC: NX_Q9Y2I1

  • Chr Location
    3p21.1; chr3:52455508-52493072 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    35
  • Gene trapped
    30
  • Targeted
    5
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000035875 VEGA Gene Model | MGI Sequence Detail 46017 C57BL/6J ±  kb
transcript OTTMUST00000091988 VEGA | MGI Sequence Detail 5559 Not Applicable  
polypeptide OTTMUSP00000050743 VEGA | MGI Sequence Detail 1593 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    203 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    cDNA 27
    Other 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1921365, MGI:1924216, MGI:2145818
References
more
  • Summaries
    All 41
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:66342 Alahari SK, et al., Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration. J Cell Biol. 2000 Dec 11;151(6):1141-54
  • Latest
    J:175792 Jelcick AS, et al., Genetic variations strongly influence phenotypic outcome in the mouse retina. PLoS One. 2011;6(7):e21858

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory