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Afg3l1 Gene Detail
Summary
  • Symbol
    Afg3l1
  • Name
    AFG3-like AAA ATPase 1
  • Synonyms
    1700047G05Rik, 3110061K15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928277
    NCBI Gene: 114896
Location & Maps
more
  • Sequence Map
    Chr8:123477903-123503916 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      26014 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 72.10 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    AFG3L1P, AFG3 like matrix AAA peptidase subunit 1, pseudogene
  • Vertebrate Orthologs
    5
  • Human Ortholog
    AFG3L1P, AFG3 like matrix AAA peptidase subunit 1, pseudogene
    Orthology source: HGNC
  • Synonyms
    AFG3, AFG3L1
  • Links
    NCBI Gene ID: 172

  • Chr Location
    16q24.3; chr16:89972580-90000787 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Gene trapped
    1
  • Targeted
    3
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031059 VEGA Gene Model | MGI Sequence Detail 26014 C57BL/6J ±  kb
transcript OTTMUST00000076944 VEGA | MGI Sequence Detail 4227 Not Applicable  
polypeptide OTTMUSP00000040571 VEGA | MGI Sequence Detail 789 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    106 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 121
    Genomic 1
    cDNA 120

    Microarray probesets 5
Other
Accession IDs
less
MGI:1914568, MGI:1920450
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:164484 Koppen M, et al., Autocatalytic processing of m-AAA protease subunits in mitochondria. Mol Biol Cell. 2009 Oct;20(19):4216-24

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory