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Mrps22 Gene Detail
Summary
  • Symbol
    Mrps22
  • Name
    mitochondrial ribosomal protein S22
  • Synonyms
    3100002P07Rik, Rpms22
  • Feature Type
    protein coding gene
  • IDs
    MGI:1928137
    NCBI Gene: 64655
Location & Maps
more
  • Sequence Map
    Chr9:98588730-98601660 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12931 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    MRPS22, mitochondrial ribosomal protein S22
  • Vertebrate Orthologs
    11
  • Human Ortholog
    MRPS22, mitochondrial ribosomal protein S22
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C3orf5, COXPD5, GIBT, GK002, MRP-S22, RPMS22
  • Links
    NCBI Gene ID: 56945
    neXtProt AC: NX_P82650

  • Chr Location
    3q23; chr3:139343994-139357129 (+)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human MRPS22 associations

Human Disease Mouse Models
       Combined Oxidative Phosphorylation Deficiency 5; COXPD5   OMIM: 611719
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    4
  • Chemically induced (other)
    1
  • Targeted
    3
  • Genomic Mutations
    1 involving Mrps22
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000047584 VEGA Gene Model | MGI Sequence Detail 12931 C57BL/6J ±  kb
transcript OTTMUST00000122720 VEGA | MGI Sequence Detail 1197 Not Applicable  
polypeptide OTTMUSP00000067229 VEGA | MGI Sequence Detail 359 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    197 from dbSNP Build 137
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010630 28S ribosomal protein S22, mitochondrial
  • InterPro Domains
    IPR019374 Ribosomal protein S22, mitochondrial
Molecular
Reagents
less
  • All nucleic 44
    cDNA 44

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913568
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:65190 Koc EC, et al., A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins. J Biol Chem. 2000 Oct 20;275(42):32585-91
  • Latest
    J:210665 Shi F, et al., A piggyBac insertion disrupts Foxl2 expression that mimics BPES syndrome in mice. Hum Mol Genet. 2014 Jul 15;23(14):3792-800

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory