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Tspan4
Gene Detail
 Symbol
Name
ID
Tspan4
tetraspanin 4
MGI:1928097
Synonyms D130042I01Rik, NAG-2, novel antigen 2, Tm4sf7, Tspan-4
Feature Type protein coding gene
Genetic Map
Chromosome 7
86.83 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:141475240-141493427 bp, + strand
From VEGA annotation of GRCm38

  18188 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2453  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: tetraspanin
Gene Tree: Tspan4

Human
homologs
Human Homolog TSPAN4, tetraspanin 4
NCBI Gene ID 7106
neXtProt AC  NX_O14817
Human Synonyms  NAG2, NAG-2, TETRASPAN, TM4SF7, TSPAN-4
Human Chr (Location)  11p15.5; chr11:842824-867116 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(16) : Gene trapped(12) Targeted(4)
Interactions
Tspan4 interacts with 65 markers (Mir1a-1, Mir1a-2, Mir29a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process protein complex assembly
Component integral component of membrane, membrane, ...
Function antigen binding, integrin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (183)    Tissues (18)    Images (23)
Theiler Stages: 23
Assay TypeResults
RNA in situ 183
cDNA source data(10)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(11) cDNA(11)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000028948 (Evidence)
Ensembl Gene ModelENSMUSG00000025511 (Evidence)
Entrez Gene64540 (Evidence)
NIA Mouse Gene IndexU008964
Consensus CDS ProjectCCDS22018.1
International Mouse Knockout Project StatusTspan4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028948 VEGA Gene Model | MGI Sequence Detail 18188 C57BL/6J ±  kb
transcript OTTMUST00000071730 VEGA | MGI Sequence Detail 1466 Not Applicable 
polypeptide OTTMUSP00000036825 VEGA | MGI Sequence Detail 238 Not Applicable 

For the selected sequences
All sequences(63) RefSeq(8) UniProt(5)
Polymorphisms SNPs within 2kb(40 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000301 Tetraspanin
InterPro IPR018503 Tetraspanin, conserved site
InterPro IPR008952 Tetraspanin, EC2 domain
InterPro IPR018499 Tetraspanin/Peripherin
Protein Ontology PR:000016750 tetraspanin-4
References (Earliest) J:44052 Tachibana I, et al., NAG-2, a novel transmembrane-4 superfamily (TM4SF) protein that complexes with integrins and other TM4SF proteins. J Biol Chem. 1997 Nov 14;272(46):29181-9
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(39)
Other
accession IDs
MGI:2141916, MGI:2142025, MGI:2441940

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory