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Pex14
Gene Detail
 Symbol
Name
ID
Pex14
peroxisomal biogenesis factor 14
MGI:1927868
Synonyms Pex14p
Feature Type protein coding gene
Genetic Map
Chromosome 4
78.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr4:148960535-149099876 bp, - strand
From VEGA annotation of GRCm38

  139342 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37936  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Pex14

Human
homologs
Human Homolog PEX14, peroxisomal biogenesis factor 14
NCBI Gene ID 5195
neXtProt AC  NX_O75381
Human Synonyms  dJ734G22.2, NAPP2, PBD13A, Pex14p
Human Chr (Location)  1p36.22; chr1:10474946-10630758 (+)  GRCh38
Disease Associations  (1) Diseases Associated with Human PEX14
Alleles
and
phenotypes
All alleles(141) : Targeted(1) Gene trapped(140)
 
Homozygous disruption of this locus results in embryonic lethality.
 
Gene Ontology
(GO)
classifications
All GO classifications: (33 annotations)
Process microtubule anchoring, negative regulation of protein binding, ...
Component integral component of membrane, intracellular, ...
Function beta-tubulin binding, microtubule binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (92)    Tissues (92)    Images (18)
Theiler Stages: 22
Assay TypeResults
RNA in situ 92
cDNA source data(91)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(94) cDNA(94)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000010943 (Evidence)
Ensembl Gene ModelENSMUSG00000028975 (Evidence)
Entrez Gene56273 (Evidence)
UniGene184172
DFCITC1578555
DoTSDT.489545, DT.94168297
NIA Mouse Gene IndexU005095, U025794
Consensus CDS ProjectCCDS18950.1
International Mouse Knockout Project StatusPex14
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010943 VEGA Gene Model | MGI Sequence Detail 139342 C57BL/6J ±  kb
transcript OTTMUST00000025663 VEGA | MGI Sequence Detail 2006 Not Applicable 
polypeptide OTTMUSP00000011762 VEGA | MGI Sequence Detail 376 Not Applicable 

For the selected sequences
All sequences(34) RefSeq(2) UniProt(2)
Polymorphisms SNPs within 2kb(978 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR025655 Peroxisomal membrane protein 14
InterPro IPR006785 Peroxisome membrane anchor protein Pex14p, N-terminal
Protein Ontology PR:000012560 peroxisomal membrane protein PEX14
References (Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:180632 Ahlemeyer B, et al., Deletion of a single allele of the Pex11beta gene is sufficient to cause oxidative stress, delayed differentiation and neuronal death in mouse brain. Dis Model Mech. 2012 Jan;5(1):125-40
All references(43)
Other
accession IDs
MGI:2140717

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory