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Zfp280b Gene Detail
Summary
  • Symbol
    Zfp280b
  • Name
    zinc finger protein 280B
  • Synonyms
    D10Jhu82e, Suhw2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927865
    NCBI Gene: 64453
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:76032401-76042970 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 38.67 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    20 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927865
protein coding gene Chr10:76032401-76043234 (.)
129S1/SvImJ MGP_129S1SvImJ_G0017375
protein coding gene Chr10:76245301-76255139 (+)
A/J MGP_AJ_G0017352
protein coding gene Chr10:73618172-73628661 (+)
AKR/J MGP_AKRJ_G0017313
protein coding gene Chr10:75599012-75610098 (+)
BALB/cJ MGP_BALBcJ_G0017312
protein coding gene Chr10:73818168-73831256 (+)
C3H/HeJ MGP_C3HHeJ_G0017136
protein coding gene Chr10:75649726-75661997 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017770
protein coding gene Chr10:78938041-78949626 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015460
protein coding gene Chr10:70066532-70076918 (+)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0017108
protein coding gene Chr10:82022133-82035379 (+)
DBA/2J MGP_DBA2J_G0017213
protein coding gene Chr10:72916680-72939994 (+)
FVB/NJ MGP_FVBNJ_G0035256
protein coding gene ChrX:508126-518132 (-)
LP/J MGP_LPJ_G0017286
protein coding gene Chr10:76749388-76762046 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017234
protein coding gene Chr10:84101815-84113263 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017809
protein coding gene Chr10:75644652-75655777 (+)
PWK/PhJ MGP_PWKPhJ_G0016490
protein coding gene Chr10:72748493-72760133 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016273
protein coding gene Chr10:74881921-74892526 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    ZNF280B, zinc finger protein 280B
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ZNF280B, zinc finger protein 280B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    5'OY11.1, D87009.C22.3, SUHW2, ZNF279, ZNF632
  • Links
    NCBI Gene ID: 140883
    neXtProt AC: NX_Q86YH2
    UniProt: Q86YH2

  • Chr Location
    22q11.22; chr22:22484421-22509187 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 64453 NCBI Gene Model | MGI Sequence Detail 10570 C57BL/6J ±  kb
transcript NM_177475 RefSeq | MGI Sequence Detail 4874 C57BL/6  
polypeptide NP_803426 RefSeq | MGI Sequence Detail 534 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR025243 Domain of unknown function DUF4195
    IPR013087 Zinc finger C2H2-type
Molecular
Reagents
less
  • All nucleic 73
    Genomic 1
    cDNA 71
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory