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Defb4
Gene Detail
Symbol

Name
ID
Defb4
defensin beta 4
MGI:1927667
Synonyms
2310001F05Rik, MBD-4
Feature Type
protein coding gene
Genetic Map
Chromosome 8
10.35 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(5)
Sequence Map
Chr8:19198706-19201545 bp, + strand
From VEGA annotation of GRCm38

  2840 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
Protein SuperFamily: crotamine
Gene Tree: Defb4
Mutations,
alleles, and
phenotypes
Incidental mutations (data from Mutagenetix , APF )
Interactions
Defb4 interacts with 49 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process defense response, defense response to bacterium
Component extracellular region
External Resources: FuncBase
Expression
cDNA source data(6)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(7) cDNA(6) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000020596 (Evidence)
Ensembl Gene ModelENSMUSG00000059230 (Evidence)
Entrez Gene56519 (Evidence)
UniGene45276
DFCITC1587115
DoTSDT.60105145
Consensus CDS ProjectCCDS40254.1
International Mouse Knockout Project StatusDefb4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020596 VEGA Gene Model | MGI Sequence Detail 2840 C57BL/6J ±  kb
transcript OTTMUST00000048800 VEGA | MGI Sequence Detail 454 Not Applicable 
polypeptide OTTMUSP00000022475 VEGA | MGI Sequence Detail 63 Not Applicable 

For the selected sequences
All sequences(26) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(14 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR006080 Beta defensin/Neutrophil defensin
InterPro IPR001855 Beta defensin type
Protein Ontology PR:000034745 beta-defensin 4
References
(Earliest) J:65459 Jia HP, et al., A novel murine beta -defensin expressed in tongue, esophagus, and trachea. J Biol Chem. 2000 Oct 27;275(43):33314-20
(Latest) J:82526 Morrison GM, et al., Signal Sequence Conservation and Mature Peptide Divergence Within Subgroups of the Murine beta-Defensin Gene Family. Mol Biol Evol. 2003 Mar;20(3):460-70
All references(24)
Other
accession IDs
MGI:1913598

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory