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Defb4 Gene Detail
Summary
  • Symbol
    Defb4
  • Name
    defensin beta 4
  • Synonyms
    2310001F05Rik, MBD-4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927667
    NCBI Gene: 56519
Location & Maps
more
  • Sequence Map
    Chr8:19198706-19201545 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2840 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 10.35 cM, cytoband A3
  • Mapping Data
    5 experiments
Homology
less
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020596 VEGA Gene Model | MGI Sequence Detail 2840 C57BL/6J ±  kb
transcript OTTMUST00000048800 VEGA | MGI Sequence Detail 454 Not Applicable  
polypeptide OTTMUSP00000022475 VEGA | MGI Sequence Detail 63 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    13 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000034745 beta-defensin 4
  • InterPro Domains
    IPR001855 Beta defensin type
Molecular
Reagents
less
  • All nucleic 7
    cDNA 6
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913598
References
more
  • Summaries
    All 25
    Gene Ontology 5
  • Earliest
    J:65459 Jia HP, et al., A novel murine beta -defensin expressed in tongue, esophagus, and trachea. J Biol Chem. 2000 Oct 27;275(43):33314-20
  • Latest
    J:199719 Kolar SS, et al., Protective role of murine beta-defensins 3 and 4 and cathelin-related antimicrobial peptide in Fusarium solani keratitis. Infect Immun. 2013 Aug;81(8):2669-77

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory