Defb4
Gene Detail

Symbol Name ID

Defb4 defensin beta 4 MGI:1927667

Synonyms

2310001F05Rik, MBD-4

Feature Type

protein coding gene

Genetic Map

Chromosome 8

10.35 cM, cytoband A3
Detailed Genetic Map ± 1 cM


Mapping data(5)

Sequence Map

Chr8:19198706-19201545 bp, + strand From VEGA annotation of GRCm38   2840 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

Protein SuperFamily: crotamine
Gene Tree: Defb4

Gene Ontology (GO) classifications

All GO classifications: (5 annotations)

Process	defense response, defense response to bacterium
Component	extracellular region

External Resources: FuncBase

Expression

cDNA source data(6)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(7) cDNA(6) Primer pair(1)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000020596 (Evidence)
Ensembl Gene Model	ENSMUSG00000059230 (Evidence)
Entrez Gene	56519 (Evidence)
UniGene	45276
DFCI	TC1587115
DoTS	DT.60105145
Consensus CDS Project	CCDS40254.1
International Mouse Knockout Project Status	Defb4

Sequences

Length	Strain/Species
genomic	OTTMUSG00000020596	VEGA Gene Model | MGI Sequence Detail	2840	C57BL/6J
transcript	OTTMUST00000048800	VEGA | MGI Sequence Detail	454	Not Applicable
polypeptide	OTTMUSP00000022475	VEGA | MGI Sequence Detail	63	Not Applicable

All sequences(25) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(7 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR006080	Beta defensin/Neutrophil defensin
InterPro	IPR001855	Beta defensin type
Protein Ontology	PR:000034745	beta-defensin 4

References

(Earliest) J:65459 Jia HP, et al., A novel murine beta -defensin expressed in tongue, esophagus, and trachea. J Biol Chem. 2000 Oct 27;275(43):33314-20
(Latest) J:82526 Morrison GM, et al., Signal Sequence Conservation and Mature Peptide Divergence Within Subgroups of the Murine beta-Defensin Gene Family. Mol Biol Evol. 2003 Mar;20(3):460-70
All references(24)

Other accession IDs

MGI:1913598