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Dhx38 Gene Detail
Summary
  • Symbol
    Dhx38
  • Name
    DEAH (Asp-Glu-Ala-His) box polypeptide 38
  • Synonyms
    5730550P09Rik, Ddx38, Prp16
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927617
    NCBI Gene: 64340
  • Gene Overview
    MyGene.info: DHX38
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:109548011-109565861 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 57.09 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    133 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927617
protein coding gene Chr8:109548003-109565861 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034106
protein coding gene Chr8:112148208-112165776 (-)
A/J MGP_AJ_G0034086
protein coding gene Chr8:107589072-107606636 (-)
AKR/J MGP_AKRJ_G0034012
protein coding gene Chr8:110757251-110774820 (-)
BALB/cJ MGP_BALBcJ_G0034079
protein coding gene Chr8:107813343-107830912 (-)
C3H/HeJ MGP_C3HHeJ_G0033791
protein coding gene Chr8:111467389-111484966 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034599
protein coding gene Chr8:116114050-116131614 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031541
protein coding gene Chr8:100641359-100658636 (-)
CAST/EiJ MGP_CASTEiJ_G0033118
protein coding gene Chr8:111064026-111081686 (-)
CBA/J MGP_CBAJ_G0033764
protein coding gene Chr8:120009015-120026585 (-)
DBA/2J MGP_DBA2J_G0033919
protein coding gene Chr8:106930419-106948179 (-)
FVB/NJ MGP_FVBNJ_G0033864
protein coding gene Chr8:105880205-105897783 (-)
LP/J MGP_LPJ_G0034010
protein coding gene Chr8:112323644-112342796 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033909
protein coding gene Chr8:123029801-123047365 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034618
protein coding gene Chr8:110720003-110737572 (-)
PWK/PhJ MGP_PWKPhJ_G0032820
protein coding gene Chr8:106493658-106511380 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032659
protein coding gene Chr8:109402766-109420514 (-)
WSB/EiJ MGP_WSBEiJ_G0033233
protein coding gene Chr8:111402424-111421075 (-)



Homology
more
  • Human Ortholog
    DHX38, DEAH-box helicase 38
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DHX38, DEAH-box helicase 38
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DDX38, PRP16, PRPF16
  • Links
    NCBI Gene ID: 9785
    neXtProt AC: NX_Q92620
    UniProt: Q92620

  • Chr Location
    16q22.2; chr16:72093665-72112912 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 8512
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DHX38
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037993 Ensembl Gene Model | MGI Sequence Detail 17851 C57BL/6J ±  kb
transcript ENSMUST00000042601 Ensembl | MGI Sequence Detail 4463 Not Applicable  
polypeptide ENSMUSP00000047865 Ensembl | MGI Sequence Detail 1228 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • InterPro Domains
    IPR011545 DEAD/DEAH box helicase domain
    IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
    IPR011709 Domain of unknown function DUF1605
    IPR007502 Helicase-associated domain
    IPR001650 Helicase, C-terminal
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 97
    cDNA 97

    Microarray probesets 3
Other
Accession IDs
less
MGI:1917918, MGI:2142512, MGI:2142797
References
more
  • Summaries
    All 31
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:62630 Chu CC, et al., Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis. Mol Immunol. 1998 Jun;35(8):487-502
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory