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Gprc5b
Gene Detail
Symbol

Name
ID
Gprc5b
G protein-coupled receptor, family C, group 5, member B
MGI:1927596
Synonyms
hypothetical protein, clone 2-63
Feature Type
protein coding gene
Genetic Map
Chromosome 7
63.72 cM, cytoband F3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr7:118972040-118995211 bp, - strand
From NCBI annotation of GRCm38

  23172 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:9435  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: GPRC5B
Protein SuperFamily: retinoic acid-induced G protein-coupled receptor
Gene Tree: Gprc5b

Human
homologs
GPRC5B, G protein-coupled receptor, class C, group 5, member B
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 51704
neXtProt AC: NX_Q9NZH0

Human Synonyms: RAIG2, RAIG-2

Human Chr (Location): 16p12; chr16:19858971-19886045 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(4) : Gene trapped(1) Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a reporter allele exhibit partial neonatal and postnatal lethality, altered spontaneous activity pattern, and decreased response to a new environment.
 
Interactions
Gprc5b interacts with 339 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (6 records)
Data Summary: Results (52)    Tissues (38)    Images (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 27
RT-PCR 25
cDNA source data(5)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: Xenbase gprc5b    NEW 
Molecular
reagents
All nucleic(6) cDNA(5) Primer pair(1)
Microarray probesets(6)
Other database
links
Ensembl Gene Model ENSMUSG00000008734 (Evidence)
Entrez Gene 64297 (Evidence)
NIA Mouse Gene Index U029178
Consensus CDS Project CCDS21777.1
International Mouse Phenotyping Consortium Status Gprc5b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 64297 NCBI Gene Model | MGI Sequence Detail 23172 C57BL/6J ±  kb
transcript NM_022420 RefSeq | MGI Sequence Detail 4525 C57BL/6 
polypeptide Q923Z0 UniProt | EBI | MGI Sequence Detail 410 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(224 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR017978 GPCR, family 3, C-terminal
Protein Ontology PR:000008195 G-protein coupled receptor family C group 5 member B
Graphical View of Protein Domain Structure
References
(Earliest) J:64911 Inoue S, et al., Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains. Biochem Biophys Res Commun. 2000 Feb 16;268(2):553-61
(Latest) J:204990 Kurabayashi N, et al., The G protein-coupled receptor GPRC5B contributes to neurogenesis in the developing mouse neocortex. Development. 2013 Nov;140(21):4335-46
All references(37)
Other
accession IDs
MGI:2142210

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Funding Information
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory