About   Help   FAQ
Dipk1b Gene Detail
Summary
  • Symbol
    Dipk1b
  • Name
    divergent protein kinase domain 1B
  • Synonyms
    B230317C12Rik, Fam69b, PIP49
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927576
    NCBI Gene: 56279
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:26628457-26636497 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 18.97 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    89 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927576
protein coding gene Chr2:26628457-26636497 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025494
protein coding gene Chr2:24601001-24609041 (+)
A/J MGP_AJ_G0025471
protein coding gene Chr2:23650277-23658305 (+)
AKR/J MGP_AKRJ_G0025441
protein coding gene Chr2:24420491-24428519 (+)
BALB/cJ MGP_BALBcJ_G0025467
protein coding gene Chr2:23760844-23768967 (+)
C3H/HeJ MGP_C3HHeJ_G0025228
protein coding gene Chr2:24375118-24383158 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025911
protein coding gene Chr2:25399492-25407384 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023322
protein coding gene Chr2:22526045-22533836 (+)
CAST/EiJ MGP_CASTEiJ_G0024691
protein coding gene Chr2:24253071-24260927 (+)
CBA/J MGP_CBAJ_G0025206
protein coding gene Chr2:26237157-26248274 (+)
DBA/2J MGP_DBA2J_G0025339
protein coding gene Chr2:23468885-23476913 (+)
FVB/NJ MGP_FVBNJ_G0025301
protein coding gene Chr2:23228042-23236082 (+)
LP/J MGP_LPJ_G0025425
protein coding gene Chr2:24534510-24542550 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025332
protein coding gene Chr2:26377521-26385561 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025970
protein coding gene Chr2:24372519-24380559 (+)
PWK/PhJ MGP_PWKPhJ_G0024439
protein coding gene Chr2:23279071-23287199 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024239
protein coding gene Chr2:24510028-24517791 (+)
WSB/EiJ MGP_WSBEiJ_G0024760
protein coding gene Chr2:24481119-24489159 (+)



Homology
more
  • Human Ortholog
    DIPK1B, divergent protein kinase domain 1B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DIPK1B, divergent protein kinase domain 1B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C9orf136, FAM69B, pp6977
  • Links
    NCBI Gene ID: 138311
    neXtProt AC: NX_Q5VUD6
    UniProt: Q5VUD6

  • Chr Location
    9q34.3; chr9:136712572-136724718 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 10516
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DIPK1B
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56279 NCBI Gene Model | MGI Sequence Detail 8041 C57BL/6J ±  kb
transcript NM_019833 RefSeq | MGI Sequence Detail 1636 C57BL/6  
polypeptide Q99ML4 UniProt | EBI | MGI Sequence Detail 431 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 30
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139324
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 5
  • Earliest
    J:64911 Inoue S, et al., Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains. Biochem Biophys Res Commun. 2000 Feb 16;268(2):553-61
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/13/2019
MGI 6.13
The Jackson Laboratory