About   Help   FAQ
Osbpl1a Gene Detail
Summary
  • Symbol
    Osbpl1a
  • Name
    oxysterol binding protein-like 1A
  • Synonyms
    G430090F17Rik, LOC328902
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927551
    NCBI Gene: 64291
  • Gene Overview
    MyGene.info: OSBPL1A
  • Alliance
  • Transcription Start Sites
    24 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:12755314-12941841 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 18, 6.78 cM, cytoband A2
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    832 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927551
protein coding gene Chr18:12755305-12941866 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024163
protein coding gene Chr18:9960670-10164274 (-)
A/J MGP_AJ_G0024125
protein coding gene Chr18:9760873-9951081 (-)
AKR/J MGP_AKRJ_G0024092
protein coding gene Chr18:10062243-10255361 (-)
BALB/cJ MGP_BALBcJ_G0024124
protein coding gene Chr18:9715144-9909532 (-)
C3H/HeJ MGP_C3HHeJ_G0023891
protein coding gene Chr18:9946877-10140891 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024569
protein coding gene Chr18:10452930-10660416 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022009
protein coding gene Chr18:9332446-9518636 (-)
CAST/EiJ MGP_CASTEiJ_G0023368
protein coding gene Chr18:9824399-10039439 (-)
CBA/J MGP_CBAJ_G0023863
protein coding gene Chr18:10600114-10817495 (-)
DBA/2J MGP_DBA2J_G0023992
protein coding gene Chr18:9602020-9786697 (-)
FVB/NJ MGP_FVBNJ_G0023957
protein coding gene Chr18:9476276-9662793 (-)
LP/J MGP_LPJ_G0024075
protein coding gene Chr18:10038936-10245942 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023986
protein coding gene Chr18:10749269-10950540 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024615
protein coding gene Chr18:9833089-10019451 (-)
PWK/PhJ MGP_PWKPhJ_G0023114
protein coding gene Chr18:9671889-9871550 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022923
protein coding gene Chr18:10090836-10300802 (-)
WSB/EiJ MGP_WSBEiJ_G0023434
protein coding gene Chr18:9826014-10030142 (-)



Homology
more
  • Human Ortholog
    OSBPL1A, oxysterol binding protein like 1A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    OSBPL1A, oxysterol binding protein like 1A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ORP1, ORP-1, OSBPL1B
  • Links
    NCBI Gene ID: 114876
    neXtProt AC: NX_Q9BXW6
    UniProt: Q9BXW6

  • Chr Location
    18q11.2; chr18:24162045-24397882 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044252 Ensembl Gene Model | MGI Sequence Detail 186528 C57BL/6J ±  kb
transcript ENSMUST00000074352 Ensembl | MGI Sequence Detail 3956 Not Applicable  
polypeptide ENSMUSP00000073957 Ensembl | MGI Sequence Detail 950 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 108
    cDNA 106
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:2685599
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:78568 Anniss AM, et al., An oxysterol-binding protein family identified in the mouse. DNA Cell Biol. 2002 Aug;21(8):571-80
  • Latest
    J:186172 Courtney SC, et al., Identification of novel host cell binding partners of oas1b, the protein conferring resistance to flavivirus-induced disease in mice. J Virol. 2012 Aug;86(15):7953-63

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/06/2018
MGI 6.13
The Jackson Laboratory