Rgs17 Gene Detail

Summary

• Symbol
  Rgs17
• Name
  regulator of G-protein signaling 17
• Synonyms
  6430507P11Rik, RGSZ2

• Feature Type
  protein coding gene
• IDs
  MGI:1927469
  NCBI Gene: 56533
• Gene Overview
  MyGene.info: RGS17

Location & Maps

• Sequence Map
  Chr10:5825663-5922386 bp, - strand
• From VEGA annotation of GRCm38
  

  Mouse Genome Browser
  
  

• Download
  Sequence
    96724 bp   ±  kb flank
  
  
• Genome Browsers
  VEGA | Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 10, 1.91 cM
• Mapping Data
  2 experiments

Homology

• Human Ortholog
  RGS17, regulator of G protein signaling 17

• Vertebrate Orthologs
  9

• Human Ortholog
  RGS17, regulator of G protein signaling 17
  Orthology source: HomoloGene, HGNC
• Synonyms
  hRGS17, RGS-17, RGSZ2
• Links
  HGNC:14088

  NCBI Gene ID: 26575

  neXtProt AC: NX_Q9UGC6

  UniProt: Q9UGC6

  
  
• Chr Location
  6q25.2; chr6:153010891-153131284 (-)  GRCh38.p7

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• HomoloGene
  Vertebrate Homology Class 8242
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  
• HCOP
  human homology predictions: RGS17
• Protein SuperFamily
  regulator of G protein signaling, RGS4 type
• Gene Tree
  Rgs17
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  9 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  11
• GO References
  3

• External Resources
  FuncBase

Expression

• cDNA Data
  22
• Literature Summary
  1

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase rgs17
  ZFIN rgs17

Interactions

• Rgs17 interacts with 500 markers (Mir1b, Mir7-1, Mir7-2, ...) View All

Sequences &
Gene Models

• All Sequences
  40
• RefSeq
  6
• UniProt
  6
• CCDS
  CCDS56685.1, CCDS56686.1
• UniGene
  44606

• VEGA
  OTTMUSG00000027502 (Evidence)
• Ensembl
  ENSMUSG00000019775 (Evidence)
• NCBI Gene
  56533

Representative Sequences			Length	Strain/Species
genomic	OTTMUSG00000027502	VEGA Gene Model | MGI Sequence Detail	96724	C57BL/6J
transcript	OTTMUST00000068071	VEGA | MGI Sequence Detail	8107	Not Applicable
polypeptide	OTTMUSP00000034347	VEGA | MGI Sequence Detail	210	Not Applicable

Polymorphisms

• SNPs within 2kb
  919 from dbSNP Build 142

• RFLP
  1

Protein
Information

• UniProt
  6 Sequences
• Protein Ontology
  PR:000013951 regulator of G-protein signaling 17
  (term hierarchy)
• InterPro Domains
  IPR016137 RGS domain
  IPR024066 RGS, subdomain 1

Molecular
Reagents

• All nucleic 23

  cDNA 23

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:1915239

References

• Summaries
  All 29

  Developmental Gene Expression 1

  Gene Ontology 3

  Phenotypes 2
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55