Rgs17 Gene Detail

Summary

• Symbol
  Rgs17
• Name
  regulator of G-protein signaling 17
• Synonyms
  6430507P11Rik, RGSZ2

• Feature Type
  protein coding gene
• IDs
  MGI:1927469
  NCBI Gene: 56533
• Gene Overview
  MyGene.info: RGS17
• Alliance
  gene page
• Transcription Start Sites
  5 TSS

Location &
Maps

• Sequence Map
  Chr10:5825663-5922400 bp, - strand
• From NCBI annotation of GRCm38
  

  View this region in JBrowse
  
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 10, 1.91 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  919 from dbSNP Build 142
• Strain Annotations
  18
• RFLP
  1

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1927469	protein coding gene	Chr10:5825663-5922400 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0016988	protein coding gene	Chr10:2917855-3028009 (-)
A/J	MGP_AJ_G0016966	protein coding gene	Chr10:2747487-2851707 (-)
AKR/J	MGP_AKRJ_G0016931	protein coding gene	Chr10:2773515-2875708 (-)
BALB/cJ	MGP_BALBcJ_G0016924	protein coding gene	Chr10:2737322-2828492 (-)
C3H/HeJ	MGP_C3HHeJ_G0016749	protein coding gene	Chr10:2882646-2993335 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0017387	protein coding gene	Chr10:3003770-3116198 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015093	protein coding gene	Chr10:2495868-2586316 (-)
CAST/EiJ	MGP_CASTEiJ_G0016331	protein coding gene	Chr10:2923025-3033899 (-)
CBA/J	MGP_CBAJ_G0016721	protein coding gene	Chr10:3090909-3209290 (-)
DBA/2J	MGP_DBA2J_G0016829	protein coding gene	Chr10:2730828-2829766 (-)
FVB/NJ	MGP_FVBNJ_G0016824	protein coding gene	Chr10:2679803-2775294 (-)
LP/J	MGP_LPJ_G0016904	protein coding gene	Chr10:2844628-2944363 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0016855	protein coding gene	Chr10:2951523-3059492 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017424	protein coding gene	Chr10:2790218-2888337 (-)
PWK/PhJ	MGP_PWKPhJ_G0016117	protein coding gene	Chr10:2744863-2849299 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0015899	protein coding gene	Chr10:3003651-3094730 (-)
WSB/EiJ	MGP_WSBEiJ_G0016393	protein coding gene	Chr10:2866305-2966683 (-)

Homology

• Human Ortholog
  RGS17, regulator of G protein signaling 17

• Vertebrate Orthologs
  9

• Human Ortholog
  RGS17, regulator of G protein signaling 17
  Orthology source: HGNC, HomoloGene
• Synonyms
  hRGS17, RGS-17, RGSZ2
• Links
  HGNC:14088

  NCBI Gene ID: 26575

  neXtProt AC: NX_Q9UGC6

  UniProt: Q9UGC6

  
  
• Chr Location
  6q25.2; chr6:153010891-153131284 (-)  GRCh38.p7

---

• HomoloGene
  Vertebrate Homology Class 8242
  1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  
• HCOP
  human homology predictions: RGS17
• Protein SuperFamily
  regulator of G protein signaling, RGS4 type
• Gene Tree
  Rgs17
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  2 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  9
• GO References
  2

• External Resources
  FuncBase

Expression

• cDNA Data
  23
• Literature Summary
  1

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase rgs17
  ZFIN rgs17

Interactions

• Rgs17 interacts with 500 markers (Mir1b, Mir7-1, Mir7-2, ...) View All

Sequences &
Gene Models

• All Sequences
  51
• RefSeq
  6
• UniProt
  6
• CCDS
  CCDS56685.1, CCDS56686.1
• UniGene
  44606

• Ensembl
  ENSMUSG00000019775 (Evidence)
• NCBI Gene
  56533

Representative Sequences			Length	Strain/Species
genomic	56533	NCBI Gene Model | MGI Sequence Detail	96738	C57BL/6J
transcript	NM_001161822	RefSeq | MGI Sequence Detail	8191	C57BL/6
polypeptide	Q9QZB0	UniProt | EBI | MGI Sequence Detail	210	Not Applicable

Protein
Information

• UniProt
  6 Sequences
• InterPro Domains
  IPR016137 RGS domain
  IPR036305 RGS domain superfamily
  IPR024066 RGS, subdomain 1/3

Molecular
Reagents

• All nucleic 24

  cDNA 24

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:1915239

References

• Summaries
  All 27

  Developmental Gene Expression 1

  Gene Ontology 2

  Phenotypes 2
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55

TSS for Rgs17:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr96570	Chr10:5922385-5922407 (-)	4 bp
Tssr96569	Chr10:5922341-5922384 (-)	37 bp
Tssr96568	Chr10:5922325-5922328 (-)	73 bp
Tssr96567	Chr10:5828097-5828108 (-)	94,297 bp
Tssr96566	Chr10:5828020-5828034 (-)	94,373 bp