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Mpp6 Gene Detail
Summary
  • Symbol
    Mpp6
  • Name
    membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
  • Synonyms
    P55t, Pals2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927340
    NCBI Gene: 56524
  • Gene Overview
    MyGene.info: MPP6
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:50110241-50198598 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 24.13 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    477 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927340
protein coding gene Chr6:50110241-50198939 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030727
protein coding gene Chr6:49198873-49294424 (+)
A/J MGP_AJ_G0030698
protein coding gene Chr6:46907042-46997876 (+)
AKR/J MGP_AKRJ_G0030623
protein coding gene Chr6:48560704-48656975 (+)
BALB/cJ MGP_BALBcJ_G0030708
protein coding gene Chr6:47250051-47339777 (+)
C3H/HeJ MGP_C3HHeJ_G0030421
protein coding gene Chr6:48584354-48674718 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031163
protein coding gene Chr6:50309074-50407032 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028370
protein coding gene Chr6:44518308-44605295 (+)
CAST/EiJ MGP_CASTEiJ_G0029825
protein coding gene Chr6:48287977-48383247 (+)
CBA/J MGP_CBAJ_G0030396
protein coding gene Chr6:52421004-52524690 (+)
DBA/2J MGP_DBA2J_G0030545
protein coding gene Chr6:46817575-46908708 (+)
FVB/NJ MGP_FVBNJ_G0030497
protein coding gene Chr6:46462536-46548741 (+)
LP/J MGP_LPJ_G0030630
protein coding gene Chr6:49160474-49251368 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030531
protein coding gene Chr6:55141506-55240150 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031192
protein coding gene Chr6:48473504-48569338 (+)
PWK/PhJ MGP_PWKPhJ_G0029537
protein coding gene Chr6:46383318-46479922 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029373
protein coding gene Chr6:47802888-47893000 (+)
WSB/EiJ MGP_WSBEiJ_G0029902
protein coding gene Chr6:48436476-48531485 (+)



Homology
more
  • Human Ortholog
    MPP6, membrane palmitoylated protein 6
  • Vertebrate Orthologs
    11
  • Human Ortholog
    MPP6, membrane palmitoylated protein 6
    Orthology source: HGNC, HomoloGene
  • Synonyms
    p55T, PALS2, VAM1, VAM-1
  • Links
    NCBI Gene ID: 51678
    neXtProt AC: NX_Q9NZW5
    UniProt: Q9NZW5

  • Chr Location
    7p15.3; chr7:24573346-24694086 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56524 NCBI Gene Model | MGI Sequence Detail 88358 C57BL/6J ±  kb
transcript NM_001361248 RefSeq | MGI Sequence Detail 2266 C57BL/6  
polypeptide Q9JLB0 UniProt | EBI | MGI Sequence Detail 553 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    Genomic 2
    cDNA 9
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:32076 Guthridge MA, et al., Induction of expression of growth-related genes by FGF-4 in mouse fibroblasts. Oncogene. 1996 Mar 21;12(6):1267-78
  • Latest
    J:183560 Terada N, et al., Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves. Mol Cell Biol. 2012 Jan;32(1):199-205

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/27/2018
MGI 6.13
The Jackson Laboratory