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Zbtb33 Gene Detail
Summary
  • Symbol
    Zbtb33
  • Name
    zinc finger and BTB domain containing 33
  • Synonyms
    E130014G12Rik, kaiso, ZNF-Kaiso
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927290
    NCBI Gene: 56805
  • Gene Overview
    MyGene.info: ZBTB33
Location & Maps
more
  • Sequence Map
    ChrX:38189812-38194684 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      4873 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    ZBTB33, zinc finger and BTB domain containing 33
  • Vertebrate Orthologs
    11
  • Human Ortholog
    ZBTB33, zinc finger and BTB domain containing 33
    Orthology source: HomoloGene
  • Synonyms
    ZNF348, ZNF-kaiso
  • Links
    NCBI Gene ID: 10009
    neXtProt AC: NX_Q86T24

  • Chr Location
    Xq23; chrX:120250752-120258396 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 4931
    1 human;1 mouse;2 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: ZBTB33
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotypes from multigenic genotypes
    8 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    2
  • Targeted
    3
Homozygous null females and hemizygous null males are viable, fertile and overtly normal with no detectable changes in blood cell composition.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017200 VEGA Gene Model | MGI Sequence Detail 4873 C57BL/6J ±  kb
transcript OTTMUST00000041655 VEGA | MGI Sequence Detail 2567 Not Applicable  
polypeptide OTTMUSP00000018710 VEGA | MGI Sequence Detail 671 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    29 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
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  • All nucleic 54
    cDNA 52
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
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MGI:2148006, MGI:2444590
References
more
  • Summaries
    All 42
    Developmental Gene Expression 7
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:54621 Daniel JM, et al., The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor. Mol Cell Biol. 1999 May;19(5):3614-23
  • Latest
    J:221199 van de Ven RA, et al., Nuclear p120-catenin regulates the anoikis resistance of mouse lobular breast cancer cells through Kaiso-dependent Wnt11 expression. Dis Model Mech. 2015 Apr;8(4):373-84

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory