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Ralb
Gene Detail
Symbol

Name
ID
Ralb
v-ral simian leukemia viral oncogene homolog B (ras related)
MGI:1927244
Synonyms
5730472O18Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 1
52.29 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:119470305-119504794 bp, - strand
From VEGA annotation of GRCm38

  34490 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:20632  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: ras protein
Gene Tree: Ralb

Human
homologs
Human Homolog RALB, v-ral simian leukemia viral oncogene homolog B
NCBI Gene ID 5899
neXtProt AC  NX_P11234
Human Chr (Location)  2q14.2; chr2:120240070-120294711 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(57) : Gene trapped(52) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele exhibit no obvious abnormalities.
 
Interactions
Ralb interacts with 152 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (18 annotations)
Process apoptotic process, cell cycle, ...
Component extracellular vesicular exosome, membrane, ...
Function GTPase activity, GTP binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (68)    Tissues (64)    Images (14)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 68
cDNA source data(84)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(85) cDNA(85)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000021776 (Evidence)
Ensembl Gene ModelENSMUSG00000004451 (Evidence)
Entrez Gene64143 (Evidence)
UniGene27832
DFCITC1587928, TC1574807
DoTSDT.101370870, DT.102541463, DT.493066, DT.94172587
NIA Mouse Gene IndexU021695
Consensus CDS ProjectCCDS15225.1
International Mouse Knockout Project StatusRalb
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021776 VEGA Gene Model | MGI Sequence Detail 34490 C57BL/6J ±  kb
transcript OTTMUST00000051693 VEGA | MGI Sequence Detail 2289 Not Applicable 
polypeptide OTTMUSP00000024377 VEGA | MGI Sequence Detail 206 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(4) UniProt(5)
Polymorphisms
SNPs within 2kb(213 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR001806 Small GTPase superfamily
InterPro IPR020849 Small GTPase superfamily, Ras type
InterPro IPR005225 Small GTP-binding protein domain
Protein Ontology PR:000013696 ras-related protein Ral-B
References
(Earliest) J:65398 Zhao Z, et al., Tissue-specific expression of GTPas RalA and RalB during embryogenesis and regulation by epithelial-mesenchymal interaction. Mech Dev. 2000 Oct;97(1-2):201-4
(Latest) J:199742 Peschard P, et al., Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis. Curr Biol. 2012 Nov 6;22(21):2063-8
All references(37)
Other
accession IDs
MGI:1917847

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory