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Zbtb21 Gene Detail
Summary
  • Symbol
    Zbtb21
  • Name
    zinc finger and BTB domain containing 21
  • Synonyms
    5430437K12Rik, B430213I24Rik, mKIAA1227, Zfp295, Znf295
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927240
    NCBI Gene: 114565
  • Gene Overview
    MyGene.info: ZBTB21
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:97945793-97962623 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 16, 57.75 cM, cytoband C3-4
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    31 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927240
protein coding gene Chr16:97945793-97962623 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023096
protein coding gene Chr16:99411352-99426545 (-)
A/J MGP_AJ_G0023064
protein coding gene Chr16:94715918-94731111 (-)
AKR/J MGP_AKRJ_G0023034
protein coding gene Chr16:97638701-97653892 (-)
BALB/cJ MGP_BALBcJ_G0023066
protein coding gene Chr16:95261504-95276721 (-)
C3H/HeJ MGP_C3HHeJ_G0022827
protein coding gene Chr16:98151888-98167081 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023513
protein coding gene Chr16:102509477-102524665 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021014
protein coding gene Chr16:92550005-92565146 (-)
CAST/EiJ MGP_CASTEiJ_G0022347
protein coding gene Chr16:98970576-98985805 (-)
CBA/J MGP_CBAJ_G0022796
protein coding gene Chr16:106965191-106980379 (-)
DBA/2J MGP_DBA2J_G0022930
protein coding gene Chr16:94576260-94591437 (-)
FVB/NJ MGP_FVBNJ_G0022904
protein coding gene Chr16:93730984-93746269 (-)
LP/J MGP_LPJ_G0023000
protein coding gene Chr16:99052584-99067777 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022925
protein coding gene Chr16:111092829-111108022 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023531
protein coding gene Chr16:98173563-98188813 (-)
PWK/PhJ MGP_PWKPhJ_G0022091
protein coding gene Chr16:94908822-94924077 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021921
protein coding gene Chr16:97673854-97689067 (-)
WSB/EiJ MGP_WSBEiJ_G0022397
protein coding gene Chr16:98451849-98467025 (-)



Homology
more
  • Human Ortholog
    ZBTB21, zinc finger and BTB domain containing 21
  • Vertebrate Orthologs
    7
  • Human Ortholog
    ZBTB21, zinc finger and BTB domain containing 21
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ZNF295
  • Links
    NCBI Gene ID: 49854
    neXtProt AC: NX_Q9ULJ3
    UniProt: Q9ULJ3

  • Chr Location
    21q22.3; chr21:41986831-42010418 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 114565 NCBI Gene Model | MGI Sequence Detail 16831 C57BL/6J ±  kb
transcript NM_175428 RefSeq | MGI Sequence Detail 6011 C57BL/6  
polypeptide NP_780637 RefSeq | MGI Sequence Detail 1094 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 41
    Genomic 1
    cDNA 36
    Primer pair 3
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1918624, MGI:2444503
References
more
  • Summaries
    All 38
    Developmental Gene Expression 4
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:262380 Watson-Scales S, et al., Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. PLoS Genet. 2018 May;14(5):e1007383

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory