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Suclg1
Gene Detail
Symbol

Name
ID
Suclg1
succinate-CoA ligase, GDP-forming, alpha subunit
MGI:1927234
Synonyms
1500000I01Rik, Sucla1
Feature Type
protein coding gene
Genetic Map
Chromosome 6
32.40 cM, cytoband C3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:73248382-73276911 bp, + strand
From VEGA annotation of GRCm38

  28530 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55785  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: succinyl-CoA synthetase, alpha subunit
Gene Tree: Suclg1

Human
homologs
Human Homolog SUCLG1, succinate-CoA ligase, alpha subunit
NCBI Gene ID 8802
neXtProt AC  NX_P53597
Human Synonyms  GALPHA, MTDPS9, SUCLA1
Human Chr (Location)  2p11.2; chr2:84423523-84459462 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human SUCLG1
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(8) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Suclg1 interacts with 117 markers (Mir9-1, Mir9-2, Mir9-3, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (24 annotations)
Process metabolic process, succinate metabolic process, ...
Component cytoplasm, extracellular vesicular exosome, ...
Function ATP citrate synthase activity, catalytic activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (132)    Tissues (102)    Images (21)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 132
cDNA source data(202)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(204) cDNA(203) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000023469 (Evidence)
Ensembl Gene ModelENSMUSG00000052738 (Evidence)
Entrez Gene56451 (Evidence)
UniGene29845
DFCITC1678781, TC1573475
DoTSDT.101170159, DT.534397, DT.101222331
NIA Mouse Gene IndexU007049
EC6.2.1.4, 6.2.1.5
Consensus CDS ProjectCCDS20246.2
International Mouse Knockout Project StatusSuclg1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023469 VEGA Gene Model | MGI Sequence Detail 28530 C57BL/6J ±  kb
transcript OTTMUST00000057082 VEGA | MGI Sequence Detail 1519 Not Applicable 
polypeptide OTTMUSP00000027499 VEGA | MGI Sequence Detail 346 Not Applicable 

For the selected sequences
All sequences(40) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(187 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR005811 ATP-citrate lyase/succinyl-CoA ligase
InterPro IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site
InterPro IPR003781 CoA-binding
InterPro IPR016040 NAD(P)-binding domain
InterPro IPR005810 Succinyl-CoA ligase, alpha subunit
InterPro IPR016102 Succinyl-CoA synthetase-like
Protein Ontology PR:000015812 succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial
References
(Earliest) J:50333 Johnson JD, et al., Genetic evidence for the expression of ATP- and GTP-specific succinyl-CoA synthetases in multicellular eucaryotes. J Biol Chem. 1998 Oct 16;273(42):27580-6
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(43)
Other
accession IDs
MGI:1915249

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory