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B4galt5 Gene Detail
Summary
  • Symbol
    B4galt5
  • Name
    UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
  • Synonyms
    9430078I07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927169
    NCBI Gene: 56336
  • Gene Overview
    MyGene.info: B4GALT5
Location & Maps
more
  • Sequence Map
    Chr2:167298444-167349183 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      50740 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 87.22 cM, cytoband H3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    B4GALT5, beta-1,4-galactosyltransferase 5
  • Vertebrate Orthologs
    9
  • Human Ortholog
    B4GALT5, beta-1,4-galactosyltransferase 5
    Orthology source: HomoloGene, HGNC
  • Synonyms
    B4Gal-T5, beta4Gal-T5, BETA4-GALT-IV, beta4GalT-V, gt-V
  • Links
    NCBI Gene ID: 9334
    neXtProt AC: NX_O43286

  • Chr Location
    20q13.1-q13.2; chr20:49632945-49713884 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    10
  • Gene trapped
    8
  • Targeted
    2
  • Incidental Mutations
Homozygous mutation of this gene results in lethality before weaning. Heterozygous mutant mice exhibit increased anxiety-like response.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000001180 VEGA Gene Model | MGI Sequence Detail 50740 C57BL/6J ±  kb
transcript OTTMUST00000002313 VEGA | MGI Sequence Detail 4210 Not Applicable  
polypeptide OTTMUSP00000001139 VEGA | MGI Sequence Detail 388 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    209 from dbSNP Build 142
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000004609 beta-1,4-galactosyltransferase 5
  • EC
  • InterPro Domains
    IPR003859 Beta-1,4-galactosyltransferase
    IPR027791 Galactosyltransferase, C-terminal
    IPR027995 Galactosyltransferase, N-terminal
    IPR029044 Nucleotide-diphospho-sugar transferases
Molecular
Reagents
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  • All nucleic 13
    cDNA 11
    Primer pair 1
    Other 1

    Microarray probesets 5
Other
Accession IDs
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MGI:1924610, MGI:2139281, MGI:2139367
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:227742 Mayo L, et al., Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation. Nat Med. 2014 Oct;20(10):1147-56

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory