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Rplp1 Gene Detail
Summary
  • Symbol
    Rplp1
  • Name
    ribosomal protein lateral stalk subunit P1
  • Synonyms
    2410042H16Rik, acidic ribosomal phosphoprotein P1, C430017H15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927099
    NCBI Gene: 56040
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr9:61820565-61821792 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 33.50 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    230 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927099
 protein coding gene Chr9:61820565-61821824 (-)
129S1/SvImJ ENSMUSG00200035567
 protein coding gene Chr9:58935238-58936496 (-)
A/J ENSMUSG00195037426
 protein coding gene Chr9:58643929-58645187 (-)
AKR/J ENSMUSG00220026027
 protein coding gene Chr9:58791239-58792497 (-)
BALB/cJ ENSMUSG00180016320
 protein coding gene Chr9:58768688-58769946 (-)
C3H/HeJ ENSMUSG00175021840
 protein coding gene Chr9:58775562-58776820 (-)
C57BL/6NJ ENSMUSG00215020546
 protein coding gene Chr9:58755870-58757128 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032318
 protein coding gene Chr9:59089611-59090846 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210036665
 protein coding gene Chr9:58870829-58872087 (-)
DBA/2J ENSMUSG00185036406
 protein coding gene Chr9:58894878-58896136 (-)
FVB/NJ ENSMUSG00205041097
 protein coding gene Chr9:59212965-59214223 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230037172
 protein coding gene Chr9:59134638-59135896 (-)
NOD/ShiLtJ ENSMUSG00190040760
 protein coding gene Chr9:58972700-58973958 (-)
NZO/HlLtJ ENSMUSG00225026976
 protein coding gene Chr9:59198648-59199906 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010021736
 protein coding gene Chr9:59975637-59976886 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    RPLP1, ribosomal protein lateral stalk subunit P1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPLP1, ribosomal protein lateral stalk subunit P1
  • Synonyms
    LP1, P1, RPP1
  • Links
    NCBI Gene ID: 6176
    UniProt: P05386

  • Chr Location
    15q23; chr15:69452809-69456205 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice heterozygous for a knock-out allele exhibit partial postnatal lethality, male infertility, perforations in the small and large intestine, impaired hematopoiesis, and abnormal tail development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    14
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56040 NCBI Gene Model | MGI Sequence Detail 1228 C57BL/6J ±  kb
    transcript NM_018853 RefSeq | MGI Sequence Detail 468 C57BL/6  
    polypeptide P47955 UniProt | EBI | MGI Sequence Detail 114 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000014238 large ribosomal subunit protein P1
      (term hierarchy)
    • InterPro Domains
      IPR027534 Large ribosomal subunit protein P1/P2
      IPR038716 Large ribosomal subunit protein P1/P2, N-terminal domain
    • GlyGen
      P47955 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 14

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1914316, MGI:1925856
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 4
      Gene Ontology 11
      Phenotypes 8
    • Earliest
      J:63377 Abidari JM, et al., Identification of novel genes expressed during metanephric induction through single-cell library screening. Kidney Int. 2000 Jun;57(6):2221-8
    • Latest
      J:344838 Sharma S, et al., Uncovering a mammalian neural-specific poly(A) binding protein with unique properties. Genes Dev. 2023 Aug 1;37(15-16):760-777
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory