About   Help   FAQ
Cyp39a1 Gene Detail
Summary
  • Symbol
    Cyp39a1
  • Name
    cytochrome P450, family 39, subfamily a, polypeptide 1
  • Synonyms
    oxysterol 7-alpha-hydroxylase
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927096
    NCBI Gene: 56050
  • Gene Overview
    MyGene.info: CYP39A1
Location & Maps
more
  • Sequence Map
    Chr17:43667425-43751431 bp, + strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      84007 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 19.75 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CYP39A1, cytochrome P450 family 39 subfamily A member 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CYP39A1, cytochrome P450 family 39 subfamily A member 1
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 51302
    neXtProt AC: NX_Q9NYL5

  • Chr Location
    6p12.3; chr6:46549580-46652847 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    4
  • Gene trapped
    4
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023963 Ensembl Gene Model | MGI Sequence Detail 84007 C57BL/6J ±  kb
transcript ENSMUST00000170988 Ensembl | MGI Sequence Detail 3053 Not Applicable  
polypeptide ENSMUSP00000130073 Ensembl | MGI Sequence Detail 470 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    872 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 8
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 25
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:62589 Li-Hawkins J, et al., Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol. J Biol Chem. 2000 Jun 2;275(22):16543-9
  • Latest
    J:174459 Boyle MP, et al., Cell-type-specific consequences of Reelin deficiency in the mouse neocortex, hippocampus, and amygdala. J Comp Neurol. 2011 Aug 1;519(11):2061-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/12/2016
MGI 6.04
The Jackson Laboratory