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Myo1g Gene Detail
Summary
  • Symbol
    Myo1g
  • Name
    myosin IG
  • Synonyms
    E430002D17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1927091
    NCBI Gene: 246177
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:6506548-6520960 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 4.30 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1927091
protein coding gene Chr11:6506548-6520965 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018025
protein coding gene Chr11:3645799-3660195 (-)
A/J MGP_AJ_G0017998
protein coding gene Chr11:3483517-3497928 (-)
AKR/J MGP_AKRJ_G0017962
protein coding gene Chr11:3663061-3677472 (-)
BALB/cJ MGP_BALBcJ_G0017966
protein coding gene Chr11:3496226-3510630 (-)
C3H/HeJ MGP_C3HHeJ_G0017779
protein coding gene Chr11:3535134-3549587 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018418
protein coding gene Chr11:3736718-3751135 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016076
protein coding gene Chr11:3369109-3383676 (-)
CAST/EiJ MGP_CASTEiJ_G0017341
protein coding gene Chr11:3537214-3551826 (-)
CBA/J MGP_CBAJ_G0017754
protein coding gene Chr11:4160913-4175330 (-)
DBA/2J MGP_DBA2J_G0017864
protein coding gene Chr11:3387322-3401739 (-)
FVB/NJ MGP_FVBNJ_G0017856
protein coding gene Chr11:3419495-3433905 (-)
LP/J MGP_LPJ_G0017935
protein coding gene Chr11:3716424-3730828 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017882
protein coding gene Chr11:3714841-3729252 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018458
protein coding gene Chr11:3675058-3689475 (-)
PWK/PhJ MGP_PWKPhJ_G0017121
protein coding gene Chr11:3433953-3448349 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016918
protein coding gene Chr11:3619644-3634078 (-)
WSB/EiJ MGP_WSBEiJ_G0017395
protein coding gene Chr11:3499584-3513980 (-)



Homology
more
  • Human Ortholog
    MYO1G, myosin IG
  • Vertebrate Orthologs
    8
  • Human Ortholog
    MYO1G, myosin IG
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HA2, HLA-HA2, MHAG
  • Links
    NCBI Gene ID: 64005
    neXtProt AC: NX_B0I1T2
    UniProt: B0I1T2

  • Chr Location
    7p13; chr7:44962661-44979105 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit reduced B cell spreading, migration and homing and impaired T cell motility.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 246177 NCBI Gene Model | MGI Sequence Detail 14413 C57BL/6J ±  kb
transcript NM_178440 RefSeq | MGI Sequence Detail 3307 C57BL/6  
polypeptide Q5SUA5 UniProt | EBI | MGI Sequence Detail 1024 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 38
    cDNA 38

    Microarray probesets 3
Other
Accession IDs
less
MGI:2442411
References
more
  • Summaries
    All 33
    Gene Ontology 7
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:212451 Gerard A, et al., Detection of Rare Antigen-Presenting Cells through T Cell-Intrinsic Meandering Motility, Mediated by Myo1g. Cell. 2014 Jul 31;158(3):492-505

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory