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Cyb5
Gene Detail
 Symbol
Name
ID
Cyb5
cytochrome b-5
MGI:1926952
Synonyms 0610009N12Rik
Feature Type protein coding gene
Genetic Map
Chromosome 18
57.53 cM
Detailed Genetic Map ± 1 cM


Mapping data(4)
Sequence Map
Chr18:84851338-84880401 bp, + strand
From VEGA annotation of GRCm38

  29064 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:41475  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: cytochrome b5
Gene Tree: Cyb5

Human
homologs
Human Homolog CYB5A, cytochrome b5 type A (microsomal)
NCBI Gene ID 1528
neXtProt AC  NX_P00167
Human Synonyms  CYB5, MCB5
Human Chr (Location)  18q23; chr18:74253292-74292016 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human CYB5A
Alleles
and
phenotypes
All alleles(15) : Targeted(3) Gene trapped(12)
 
Mice homozygous for a conditional allele exhibit abnormal pharmacokinetics of xenobiotics following cre-mediated recombination.
 
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process fatty acid metabolic process, oxidation-reduction process, ...
Component endoplasmic reticulum, endoplasmic reticulum membrane, ...
Function enzyme binding, heme binding, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
Data Summary: Results (7)    Tissues (7)    Images (1)
Theiler Stages: 3, 4, 5
Assay TypeResults
RT-PCR 7
cDNA source data(185)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(186) cDNA(185) Primer pair(1)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000030922 (Evidence)
Ensembl Gene ModelENSMUSG00000024646 (Evidence)
Entrez Gene109672 (Evidence)
UniGene31018
DFCITC1572919
DoTSDT.87078963
NIA Mouse Gene IndexU018973
Consensus CDS ProjectCCDS29385.1
International Mouse Knockout Project StatusCyb5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030922 VEGA Gene Model | MGI Sequence Detail 29064 C57BL/6J ±  kb
transcript OTTMUST00000076513 VEGA | MGI Sequence Detail 1363 Not Applicable 
polypeptide OTTMUSP00000040293 VEGA | MGI Sequence Detail 134 Not Applicable 

For the selected sequences
All sequences(36) RefSeq(2) UniProt(5)
Polymorphisms SNPs within 2kb(245 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR018506 Cytochrome b5, heme-binding site
InterPro IPR001199 Cytochrome b5-like heme/steroid binding domain
Protein Ontology PR:000006078 cytochrome b5
References (Earliest) J:65999 Hanlon MR, et al., In vitro membrane-inserted conformation of the cytochrome b5 tail. Biochem J. 2000 Nov 15;352 Pt 1:117-24
(Latest) J:196604 Yagita Y, et al., Tail-anchored PEX26 targets peroxisomes via a PEX19-dependent and TRC40-independent class I pathway. J Cell Biol. 2013 Mar 4;200(5):651-66
All references(42)
Other
accession IDs
MGI:1914096

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory