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Fn3k
Gene Detail
 Symbol
Name
ID
Fn3k
fructosamine 3 kinase
MGI:1926834
Synonyms 2310074G21Rik
Feature Type protein coding gene
Genetic Map
Chromosome 11
85.38 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:121434913-121450491 bp, + strand
From VEGA annotation of GRCm38

  15579 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23336  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: ketosamine-3-kinase
Gene Tree: Fn3k

Human
homologs
Human Homolog FN3K, fructosamine 3 kinase
NCBI Gene ID 64122
neXtProt AC  NX_Q9H479
Human Chr (Location)  17q25.3; chr17:82735576-82751197 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
 
Mice homozygous for a knock-out allele grow and reproduce normally and appear healthy while cellular levels of glycated proteins and free fructoselysine are elevated in several tissues.
 
Interactions
Fn3k interacts with 310 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (44 annotations)
Process fructosamine metabolic process, phosphorylation
Component cytosol
Function 1-phosphatidylinositol-3-phosphate 4-kinase activity, 1-phosphatidylinositol-5-kinase activity, ...
External Resources: FuncBase
Expression
cDNA source data(18)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(19) cDNA(19)
Microarray probesets(6)
Other database
links
VEGA Gene ModelOTTMUSG00000004677 (Evidence)
Ensembl Gene ModelENSMUSG00000025175 (Evidence)
Entrez Gene63828 (Evidence)
UniGene266448
DFCITC1583108, TC1589468, TC1600616
DoTSDT.102559145, DT.486910
NIA Mouse Gene IndexU013690
EC2.7.1.-
Consensus CDS ProjectCCDS25776.1, CCDS25777.1
International Mouse Knockout Project StatusFn3k
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004677 VEGA Gene Model | MGI Sequence Detail 15579 C57BL/6J ±  kb
transcript OTTMUST00000010544 VEGA | MGI Sequence Detail 1047 Not Applicable 
polypeptide OTTMUSP00000004997 VEGA | MGI Sequence Detail 309 Not Applicable 

For the selected sequences
All sequences(43) RefSeq(6) UniProt(3)
Polymorphisms SNPs within 2kb(131 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016477 Fructosamine/Ketosamine-3-kinase
InterPro IPR011009 Protein kinase-like domain
Protein Ontology PR:000007582 fructosamine-3-kinase
References (Earliest) J:64795 Delpierre G, et al., Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase. Diabetes. 2000 Oct;49(10):1627-34
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(31)
Other
accession IDs
MGI:1916917

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory