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Fn3k
Gene Detail
Symbol

Name
ID
Fn3k
fructosamine 3 kinase
MGI:1926834
Synonyms
2310074G21Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
85.38 cM, cytoband E2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr11:121434913-121450491 bp, + strand
From VEGA annotation of GRCm38

  15579 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23336  Vertebrate Homology Class
1 human; 1 mouse; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken

HCOP human homology predictions: FN3K
Protein SuperFamily: ketosamine-3-kinase
Gene Tree: Fn3k

Human
homologs
FN3K, fructosamine 3 kinase
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 64122
neXtProt AC: NX_Q9H479

Human Chr (Location): 17q25.3; chr17:82735576-82751197 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from CvDC )
 
Mice homozygous for a knock-out allele grow and reproduce normally and appear healthy while cellular levels of glycated proteins and free fructoselysine are elevated in several tissues.
 
Interactions
Fn3k interacts with 310 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
cDNA source data(18)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase fn3k    NEW 
Molecular
reagents
All nucleic(19) cDNA(19)
Microarray probesets(6)
Other database
links
VEGA Gene Model OTTMUSG00000004677 (Evidence)
Ensembl Gene Model ENSMUSG00000025175 (Evidence)
Entrez Gene 63828 (Evidence)
UniGene 266448
DFCI TC1589468, TC1583108, TC1600616
DoTS DT.102559145, DT.486910
NIA Mouse Gene Index U013690
EC 2.7.1.-
Consensus CDS Project CCDS25776.1, CCDS25777.1
International Mouse Phenotyping Consortium Status Fn3k
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004677 VEGA Gene Model | MGI Sequence Detail 15579 C57BL/6J ±  kb
transcript OTTMUST00000010544 VEGA | MGI Sequence Detail 1047 Not Applicable 
polypeptide OTTMUSP00000004997 VEGA | MGI Sequence Detail 309 Not Applicable 

For the selected sequences
All sequences(45) RefSeq(8) UniProt(3)
Polymorphisms
SNPs within 2kb(131 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR016477 Fructosamine/Ketosamine-3-kinase
InterPro IPR011009 Protein kinase-like domain
Protein Ontology PR:000007582 fructosamine-3-kinase
References
(Earliest) J:64795 Delpierre G, et al., Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase. Diabetes. 2000 Oct;49(10):1627-34
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(29)
Other
accession IDs
MGI:1916917

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory