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Tmeff1 Gene Detail
Summary
  • Symbol
    Tmeff1
  • Name
    transmembrane protein with EGF-like and two follistatin-like domains 1
  • Synonyms
    M7365, tomoregulin-like
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926810
    NCBI Gene: 230157
Location & Maps
more
  • Sequence Map
    Chr4:48585174-48663131 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      77958 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 26.15 cM, cytoband B2
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TMEFF1, transmembrane protein with EGF like and two follistatin like domains 1
  • Vertebrate Orthologs
    7
  • Human Ortholog
    TMEFF1, transmembrane protein with EGF like and two follistatin like domains 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    C9orf2, CT120.1, H7365, TR-1
  • Links
    NCBI Gene ID: 8577
    neXtProt AC: NX_Q8IYR6

  • Chr Location
    9q31; chr9:100473238-100577636 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    22
  • Gene trapped
    20
  • Targeted
    2
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000006852 VEGA Gene Model | MGI Sequence Detail 77958 C57BL/6J ±  kb
transcript OTTMUST00000015848 VEGA | MGI Sequence Detail 2461 Not Applicable  
polypeptide OTTMUSP00000007279 VEGA | MGI Sequence Detail 372 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    610 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 8
    Primer pair 2

    Microarray probesets 5
References
more
  • Summaries
    All 29
    Developmental Gene Expression 5
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:110088 Taniwaki T, et al., Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Dev Growth Differ. 2005 Apr;47(3):163-72

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory