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Apip Gene Detail
Summary
  • Symbol
    Apip
  • Name
    APAF1 interacting protein
  • Synonyms
    APIP2, CGI-29, Mmrp19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926788
    NCBI Gene: 56369
  • Gene Overview
    MyGene.info: APIP
Location & Maps
more
  • Sequence Map
    Chr2:103073675-103092644 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      18970 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 54.29 cM, cytoband E3
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    APIP, APAF1 interacting protein
  • Vertebrate Orthologs
    8
  • Human Ortholog
    APIP, APAF1 interacting protein
    Orthology source: HGNC, HomoloGene
  • Synonyms
    APIP2, CGI29, CGI-29, hAPIP, MMRP19
  • Links
    NCBI Gene ID: 51074
    neXtProt AC: NX_Q96GX9

  • Chr Location
    11p13; chr11:34882295-34916411 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    2 involving Apip
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000014842 VEGA Gene Model | MGI Sequence Detail 18970 C57BL/6J ±  kb
transcript OTTMUST00000035241 VEGA | MGI Sequence Detail 919 Not Applicable  
polypeptide OTTMUSP00000015746 VEGA | MGI Sequence Detail 241 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    120 from dbSNP Build 142
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000004132 methylthioribulose-1-phosphate dehydratase
  • EC
  • InterPro Domains
    IPR001303 Class II aldolase/adducin N-terminal
    IPR017714 Methylthioribulose-1-phosphate dehydratase
    IPR027514 Methylthioribulose-1-phosphate dehydratase, eukaryotes
Molecular
Reagents
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  • All nucleic 33
    cDNA 33

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 10
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory