About   Help   FAQ
Apip Gene Detail
Summary
  • Symbol
    Apip
  • Name
    APAF1 interacting protein
  • Synonyms
    APIP2, CGI-29, Mmrp19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926788
    NCBI Gene: 56369
  • Gene Overview
    MyGene.info: APIP
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:103073675-103092644 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 54.29 cM, cytoband E3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    120 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926788
protein coding gene Chr2:103073511-103092649 (.)
129S1/SvImJ MGP_129S1SvImJ_G0026201
protein coding gene Chr2:105027935-105046888 (+)
A/J MGP_AJ_G0026162
protein coding gene Chr2:100708001-100726954 (+)
AKR/J MGP_AKRJ_G0026143
protein coding gene Chr2:103430546-103449499 (+)
BALB/cJ MGP_BALBcJ_G0026171
protein coding gene Chr2:100987376-101006409 (+)
C3H/HeJ MGP_C3HHeJ_G0025922
protein coding gene Chr2:103796699-103820133 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026622
protein coding gene Chr2:108576010-108594979 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024013
protein coding gene Chr2:96374137-96392682 (+)
CAST/EiJ MGP_CASTEiJ_G0025387
protein coding gene Chr2:104242188-104261067 (+)
CBA/J MGP_CBAJ_G0025900
protein coding gene Chr2:112280037-112304460 (+)
DBA/2J MGP_DBA2J_G0026036
protein coding gene Chr2:100272407-100291655 (+)
FVB/NJ MGP_FVBNJ_G0025999
protein coding gene Chr2:99273072-99292336 (+)
LP/J MGP_LPJ_G0026140
protein coding gene Chr2:105174723-105194739 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026025
protein coding gene Chr2:116210519-116229843 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026676
protein coding gene Chr2:103646436-103665389 (+)
PWK/PhJ MGP_PWKPhJ_G0025122
protein coding gene Chr2:99768565-99787455 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024923
protein coding gene Chr2:102868876-102887646 (+)
WSB/EiJ MGP_WSBEiJ_G0025454
protein coding gene Chr2:104351277-104370259 (+)



Homology
more
  • Human Ortholog
    APIP, APAF1 interacting protein
  • Vertebrate Orthologs
    8
  • Human Ortholog
    APIP, APAF1 interacting protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    APIP2, CGI29, CGI-29, hAPIP, MMRP19
  • Links
    NCBI Gene ID: 51074
    neXtProt AC: NX_Q96GX9
    UniProt: Q96GX9

  • Chr Location
    11p13; chr11:34882295-34916411 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000010911 Ensembl Gene Model | MGI Sequence Detail 18970 C57BL/6J ±  kb
    transcript ENSMUST00000011055 Ensembl | MGI Sequence Detail 919 Not Applicable  
    polypeptide ENSMUSP00000011055 Ensembl | MGI Sequence Detail 241 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000004132 methylthioribulose-1-phosphate dehydratase
    • EC
    • InterPro Domains
      IPR001303 Class II aldolase/adducin N-terminal
      IPR036409 Class II aldolase/adducin N-terminal domain superfamily
      IPR017714 Methylthioribulose-1-phosphate dehydratase
      IPR027514 Methylthioribulose-1-phosphate dehydratase, eukaryotes
    Molecular
    Reagents
    less
    • All nucleic 34
      cDNA 34

      Microarray probesets 3
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 1
      Gene Ontology 7
      Phenotypes 12
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:262763 Hong SH, et al., APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis. Oncotarget. 2016 Apr 19;7(16):21601-17

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
    Warranty Disclaimer & Copyright Notice
    Send questions and comments to User Support.
    last database update
    11/13/2018
    MGI 6.13
    The Jackson Laboratory