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Syt9
Gene Detail
 Symbol
Name
ID
Syt9
synaptotagmin IX
MGI:1926373
Synonyms Sytv
Feature Type protein coding gene
Genetic Map
Chromosome 7
56.33 cM, cytoband F2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:107370728-107548656 bp, + strand
From VEGA annotation of GRCm38

  177929 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11062  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Protein SuperFamily: B/K protein/synaptotagmin
Gene Tree: Syt9

Human
homologs
Human Homolog SYT9, synaptotagmin IX
NCBI Gene ID 143425
neXtProt AC  NX_Q86SS6
Human Chr (Location)  11p15.4; chr11:7251950-7469045 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Gene trapped(1) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a null allele exhibit 50% embryonic lethality while cre-mediated removal of a conditional allele impairs inhibitions of postsynaptic currents.
 
Interactions
Syt9 interacts with 303 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (21 annotations)
Process positive regulation of calcium ion-dependent exocytosis, regulation of calcium ion-dependent exocytosis, ...
Component cell junction, cytoplasmic vesicle, ...
Function identical protein binding, metal ion binding, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (46)    Tissues (5)    Images (18)
Theiler Stages: 23
Assay TypeResults
RNA in situ 46
cDNA source data(22)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(22) cDNA(22)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000031453 (Evidence)
Ensembl Gene ModelENSMUSG00000062542 (Evidence)
Entrez Gene60510 (Evidence)
UniGene302793
DFCITC1581939
DoTSDT.40154139
Consensus CDS ProjectCCDS40078.1
International Mouse Knockout Project StatusSyt9
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000031453 VEGA Gene Model | MGI Sequence Detail 177929 C57BL/6J ±  kb
transcript OTTMUST00000077942 VEGA | MGI Sequence Detail 3817 Not Applicable 
polypeptide OTTMUSP00000041329 VEGA | MGI Sequence Detail 491 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(5) UniProt(3)
Polymorphisms SNPs within 2kb(1938 from dbSNP Build 137)    SNPs within 2kb including multiple locations(1940)
Protein-related
information
ResourceIDDescription
InterPro IPR000008 C2 calcium-dependent membrane targeting
InterPro IPR001565 Synaptotagmin
Protein Ontology PR:000015911 synaptotagmin-9
References (Earliest) J:62060 Fukuda M, et al., Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X. J Biol Chem. 1999 Oct 29;274(44):31421-7
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
09/16/2014
MGI 5.19
The Jackson Laboratory