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Syt5
Gene Detail
Symbol

Name
ID
Syt5
synaptotagmin V
MGI:1926368
Synonyms
SytIX
Feature Type
protein coding gene
Genetic Map
Chromosome 7
2.62 cM, cytoband A1
Detailed Genetic Map ± 1 cM


Mapping data(1)
Sequence Map
Chr7:4539768-4546567 bp, - strand
From Ensembl annotation of GRCm38

  6800 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:55722  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog

Protein SuperFamily: B/K protein/synaptotagmin
Gene Tree: Syt5

Human
homologs
Human Homolog SYT5, synaptotagmin V
NCBI Gene ID 6861
neXtProt AC  NX_O00445
Human Chr (Location)  19q; chr19:55173098-55180441 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
About 50% of mice homozygous for a knock-out allele exhibit prenatal lethality.
 
Interactions
Syt5 interacts with 70 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (20 annotations)
Process calcium ion-dependent exocytosis, transport
Component cell junction, cytoplasmic vesicle, ...
Function calcium-dependent phospholipid binding, clathrin binding, ...
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (198)    Tissues (108)    Images (35)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 198
cDNA source data(16)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(17) cDNA(16) Primer pair(1)
Microarray probesets(3)
Other database
links
Ensembl Gene ModelENSMUSG00000004961 (Evidence)
Entrez Gene53420 (Evidence)
UniGene358663
DFCITC1578504
DoTSDT.527097
NIA Mouse Gene IndexU028088
Consensus CDS ProjectCCDS20738.1
International Mouse Knockout Project StatusSyt5
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000004961 Ensembl Gene Model | MGI Sequence Detail 6800 C57BL/6J ±  kb
transcript ENSMUST00000065957 Ensembl | MGI Sequence Detail 1747 Not Applicable 
polypeptide ENSMUSP00000070322 Ensembl | MGI Sequence Detail 386 Not Applicable 

For the selected sequences
All sequences(16) RefSeq(6) UniProt(1)
Polymorphisms
SNPs within 2kb(57 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000008 C2 calcium-dependent membrane targeting
InterPro IPR001565 Synaptotagmin
Protein Ontology PR:000015907 synaptotagmin-5
References
(Earliest) J:1973 Willison K, The mouse Brachyury gene and mesoderm formation. Trends Genet. 1990 Apr;6(4):104-5
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory