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Sult2b1
Gene Detail
 Symbol
Name
ID
Sult2b1
sulfotransferase family, cytosolic, 2B, member 1
MGI:1926342
Synonyms SULT2B
Feature Type protein coding gene
Genetic Map
Chromosome 7
29.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:45729983-45759612 bp, - strand
From VEGA annotation of GRCm38

  29630 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:49487  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 2 chicken; 2 western clawed frog; 5 zebrafish

Gene Tree: Sult2b1

Human
homologs
Human Homolog SULT2B1, sulfotransferase family, cytosolic, 2B, member 1
NCBI Gene ID 6820
neXtProt AC  NX_O00204
Human Synonyms  HSST2
Human Chr (Location)  19q13.3; chr19:48552172-48599427 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(10) : Gene trapped(8) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele lack cholesterol sulfate in the dermis but otherwise appear to have normal lipid metabolism.
 
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process lipid metabolic process, steroid metabolic process, ...
Component cytoplasm, endoplasmic reticulum, ...
Function alcohol sulfotransferase activity, steroid sulfotransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (110)    Tissues (97)    Images (25)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 110
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(9) cDNA(9)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000022561 (Evidence)
Ensembl Gene ModelENSMUSG00000003271 (Evidence)
Entrez Gene54200 (Evidence)
UniGene271634
DFCITC1582256, TC1665530, TC1721789
DoTSDT.101131880, DT.529718, DT.97405246
NIA Mouse Gene IndexU086599
EC2.8.2.2
Consensus CDS ProjectCCDS21263.1
International Mouse Knockout Project StatusSult2b1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022561 VEGA Gene Model | MGI Sequence Detail 29630 C57BL/6J ±  kb
transcript OTTMUST00000054049 VEGA | MGI Sequence Detail 1242 Not Applicable 
polypeptide OTTMUSP00000025743 VEGA | MGI Sequence Detail 372 Not Applicable 

For the selected sequences
All sequences(48) RefSeq(10) UniProt(3)
Polymorphisms SNPs within 2kb(283 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR027417 P-loop containing nucleoside triphosphate hydrolase
InterPro IPR000863 Sulfotransferase domain
Protein Ontology PR:000015824 sulfotransferase family cytosolic 2B member 1
References (Earliest) J:48327 Sakakibara Y, et al., Molecular cloning, expression, and functional characterization of novel mouse sulfotransferases. Biochem Biophys Res Commun. 1998 Jun 29;247(3):681-6
(Latest) J:191344 Zhang X, et al., Cytosolic sulfotransferase 2B1b promotes hepatocyte proliferation gene expression in vivo and in vitro. Am J Physiol Gastrointest Liver Physiol. 2012 Aug 1;303(3):G344-55
All references(33)
Other
accession IDs
MGI:2141922, MGI:2142299

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory