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Plac1
Gene Detail
 Symbol
Name
ID
Plac1
placental specific protein 1
MGI:1926287
Synonyms DXWsu72e, Epcs26, Oosp2l
Feature Type protein coding gene
Genetic Map
Chromosome X
29.31 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
ChrX:53069995-53240111 bp, - strand
From VEGA annotation of GRCm38

  170117 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11039  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Plac1

Human
homologs
Human Homolog PLAC1, placenta-specific 1
NCBI Gene ID 10761
neXtProt AC  NX_Q9HBJ0
Human Synonyms  CT92, OOSP2L
Human Chr (Location)  Xq26; chrX:134565843-134658483 (-)  GRCh38
Alleles
and
phenotypes
All alleles(6) : Gene trapped(3) Targeted(3)
Incidental mutations (data from APF )
 
Female and male mice null for this gene display postnatal lethality with placental abnormalities. Female mice heterozygous for this allele display an enlarged placenta with expansion of the junctional zone.
 
Phenotype Images(5)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process multicellular organismal development, spongiotrophoblast layer developmental growth
Component extracellular region
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (8 records)
Data Summary: Results (44)    Tissues (15)    Images (22)
Theiler Stages: 11, 22, 23, 28
Assay TypeResults
RNA in situ 28
Northern blot 10
RT-PCR 6
cDNA source data(31)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(33) cDNA(31) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000017342 (Evidence)
Ensembl Gene ModelENSMUSG00000061082 (Evidence)
Entrez Gene56096 (Evidence)
UniGene274842
DFCITC1581819
DoTSDT.101367678, DT.531196
NIA Mouse Gene IndexU081688
Consensus CDS ProjectCCDS30128.1
International Mouse Knockout Project StatusPlac1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017342 VEGA Gene Model | MGI Sequence Detail 170117 C57BL/6J ±  kb
transcript OTTMUST00000097970 VEGA | MGI Sequence Detail 1041 Not Applicable 
polypeptide OTTMUSP00000054971 VEGA | MGI Sequence Detail 173 Not Applicable 

For the selected sequences
All sequences(37) RefSeq(6) UniProt(1)
Polymorphisms PCR(1) : SNPs within 2kb(715 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001507 Zona pellucida domain
Protein Ontology PR:000012815 placenta-specific protein 1
References (Earliest) J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
(Latest) J:186550 Jackman SM, et al., Plac1 (placenta-specific 1) is essential for normal placental and embryonic development. Mol Reprod Dev. 2012 Aug;79(8):564-72
All references(40)
Other
accession IDs
MGD-MRK-33931, MGI:106239, MGI:1860265

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory