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Plac1
Gene Detail
Symbol

Name
ID
Plac1
placental specific protein 1
MGI:1926287
Synonyms
DXWsu72e, Epcs26, Oosp2l
Feature Type
protein coding gene
Genetic Map
Chromosome X
29.31 cM
Detailed Genetic Map ± 1 cM


Mapping data(8)
Sequence Map
ChrX:53069995-53240111 bp, - strand
From VEGA annotation of GRCm38

  170117 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11039  Vertebrate Homology Class
1 human; 1 mouse; 2 rat; 1 rhesus macaque; 1 cattle; 1 dog

HCOP human homology predictions: PLAC1
Gene Tree: Plac1

Human
homologs
PLAC1, placenta-specific 1
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 10761
neXtProt AC: NX_Q9HBJ0

Human Synonyms: CT92, OOSP2L

Human Chr (Location): Xq26; chrX:134565838-134764312 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(6) : Gene trapped(3) Targeted(3)
Incidental mutations (data from APF )
 
Female and male mice null for this gene display postnatal lethality with placental abnormalities. Female mice heterozygous for this allele display an enlarged placenta with expansion of the junctional zone.
 
Phenotype Images(5)
Interactions
Plac1 interacts with 30 markers (Mir34a, Mir96, Mir129-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (4 annotations)
Process multicellular organismal development, spongiotrophoblast layer developmental growth
Component extracellular region
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (10 records)
Data Summary: Results (44)    Tissues (15)    Images (22)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 28
Northern blot 10
RT-PCR 6
cDNA source data(31)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(33) cDNA(31) Primer pair(2)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000017342 (Evidence)
Ensembl Gene Model ENSMUSG00000061082 (Evidence)
Entrez Gene 56096 (Evidence)
UniGene 274842
DFCI TC1581819
DoTS DT.531196, DT.101367678
NIA Mouse Gene Index U081688
Consensus CDS Project CCDS30128.1
International Mouse Phenotyping Consortium Status Plac1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017342 VEGA Gene Model | MGI Sequence Detail 170117 C57BL/6J ±  kb
transcript OTTMUST00000097971 VEGA | MGI Sequence Detail 907 Not Applicable 
polypeptide OTTMUSP00000054972 VEGA | MGI Sequence Detail 173 Not Applicable 

For the selected sequences
All sequences(39) RefSeq(8) UniProt(1)
Polymorphisms
PCR(1) : SNPs within 2kb(715 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001507 Zona pellucida domain
Protein Ontology PR:000012815 placenta-specific protein 1
References
(Earliest) J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
(Latest) J:220468 Walentin K, et al., A Grhl2-dependent gene network controls trophoblast branching morphogenesis. Development. 2015 Mar 15;142(6):1125-36
All references(41)
Other
accession IDs
MGD-MRK-33931, MGI:106239, MGI:1860265

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory