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Mrpl19 Gene Detail
Summary
  • Symbol
    Mrpl19
  • Name
    mitochondrial ribosomal protein L19
  • Synonyms
    9030416F12Rik, D6Ertd157e, MRP-L15, RLX1, Rpml15
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926274
    NCBI Gene: 56284
  • Gene Overview
    MyGene.info: MRPL19
Location & Maps
more
  • Sequence Map
    Chr6:81957851-81965958 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      8108 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 35.81 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    MRPL19, mitochondrial ribosomal protein L19
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MRPL19, mitochondrial ribosomal protein L19
    Orthology source: HGNC, HomoloGene
  • Synonyms
    L19mt, MRPL15, MRP-L15, MRP-L19, RLX1, RPML15
  • Links
    NCBI Gene ID: 9801
    neXtProt AC: NX_P49406

  • Chr Location
    2p11.1-q11.2; chr2:75646783-75662208 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 8851
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: MRPL19
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    2
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Mrpl19
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023534 VEGA Gene Model | MGI Sequence Detail 8108 C57BL/6J ±  kb
transcript OTTMUST00000057375 VEGA | MGI Sequence Detail 5000 Not Applicable  
polypeptide OTTMUSP00000027669 VEGA | MGI Sequence Detail 292 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    142 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000010581 39S ribosomal protein L19, mitochondrial
  • InterPro Domains
    IPR001857 Ribosomal protein L19
    IPR008991 Translation protein SH3-like domain
Molecular
Reagents
less
  • All nucleic 19
    cDNA 18
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1098795, MGI:1915232
References
more
  • Summaries
    All 32
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:64919 Graack HR, et al., Identification of mammalian mitochondrial ribosomal proteins (MRPs) by N-terminal sequencing of purified bovine MRPs and comparison to data bank sequences: the large subribosomal particle. Biochemistry. 1999 Dec 14;38(50):16569-77
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory